HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.-) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 2581
+	Hs
		550477 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		CHD8_HUMAN (1-2581): 0: 2337: 100.00
+	Hs
		1132738 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		160185 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CHD2_HUMAN (396-1741): 0: 812: 25.54
+	Hs
		160095 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CHD1_HUMAN (513-1808): 0: 800: 26.81
+	Hs
		1088320 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		550249 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1088545 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1101959 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		550289 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1132952 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1088582 RBM28_HUMAN (40-343): 2.16e-23: 106: 13.84		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1133008 RBM28_HUMAN (40-343): 2.16e-23: 106: 13.84		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1088405 LARP1_HUMAN (29-114): 6.38e-13: 73.8: 40.23		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1088366 ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1132769 LARP1_HUMAN (29-114): 6.38e-13: 73.8: 40.23		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1186486 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CHD9_HUMAN (2104-2481): 3.9e-107: 387: 29.62
+	Hs
		1194233 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CHD6_HUMAN (1345-2489): 5.11e-106: 383: 13.93
+	Hs
		1101977 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		CHD9_HUMAN (2104-2481): 3.9e-107: 387: 29.62
+	Hs
		550308 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		CHD9_HUMAN (2104-2481): 3.9e-107: 387: 29.62
+	Hs
		1194430 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CHD7_HUMAN (118-704): 2.38e-14: 82: 10.37