HitPredict

Interactor 1: LRAD1 (Q5T700)
Low-density lipoprotein receptor class A domain-containing protein 1
Gene: LDLRAD1

Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FXa_inhibition~Ldl_recept_a
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 273
+	Dm
		246971 Q9VBN0_DROME (35-204): 6.62e-37: 137: 17.45		TENM_DROME (4-250): 1.41e-23: 102: 12.37
+	Hs
		1355437 ST14_HUMAN (1-82): 2.47e-10: 61.2: 12.87		EGFL7_HUMAN (1-273): 1.56e-39: 140: 100.00
+	Hs
		1216966 SORL_HUMAN (21-203): 1.36e-33: 128: 20.62		EGFL6_HUMAN (62-216): 1.18e-10: 63.6: 19.53
+	Mm
		489637 PGBM_MOUSE (6-122): 1.04e-24: 102: 18.25		NID1_MOUSE (97-234): 2.84e-16: 80.6: 19.88
+	Dm
		246762 NUDEL_DROME (7-112): 2.72e-16: 78.5: 14.17		TENM_DROME (4-250): 1.41e-23: 102: 12.37
+	Hs
		957540 PGBM_HUMAN (4-122): 2.29e-25: 104: 16.67		NID2_HUMAN (4-190): 1.14e-09: 60.6: 14.49
+	Hs
		1053544 ST14_HUMAN (1-82): 2.47e-10: 61.2: 12.87		GAS6_HUMAN (54-186): 3.87e-20: 91.8: 25.18
+	Hs
		1216971 LRP1B_HUMAN (7-148): 4.31e-19: 86.6: 16.27		EGFL6_HUMAN (62-216): 1.18e-10: 63.6: 19.53
+	Hs
		341272 LRP1_HUMAN (33-136): 4.9e-12: 66.2: 14.29		FA9_HUMAN (60-191): 2e-15: 77.5: 26.95
+	Hs
		351082 LDLR_HUMAN (118-204): 2.14e-16: 78.9: 26.44		EGFL6_HUMAN (62-216): 1.18e-10: 63.6: 19.53
+	Hs
		957623 LRP2_HUMAN (118-202): 7.88e-16: 77.4: 28.24		EGFL6_HUMAN (62-216): 1.18e-10: 63.6: 19.53
+	Hs
		258286 LRP5_HUMAN (5-74): 1.49e-10: 62: 11.43		FA9_HUMAN (60-191): 2e-15: 77.5: 26.95
+	Hs
		235021 LRP1_HUMAN (33-136): 4.9e-12: 66.2: 14.29		CUBN_HUMAN (129-272): 6.69e-13: 70.6: 9.40
+	Hs
		296681 ST14_HUMAN (1-82): 2.47e-10: 61.2: 12.87		SLIT2_HUMAN (3-138): 1.42e-12: 69.5: 11.77
+	Dm
		422964 Q9W4Y4_DROME (109-204): 1.69e-09: 58.9: 19.79		NOTCH_DROME (68-172): 9.27e-10: 61: 22.32
+	Hs
		1354456 ST14_HUMAN (1-82): 2.47e-10: 61.2: 12.87		FBLN5_HUMAN (13-187): 8.52e-09: 57.5: 17.46