HitPredict

Interactor 1: G5EG62 (G5EG62)
UNC-45
Gene: unc-45

Interactor 2: HSP1 (P09446)
Heat shock protein hsp-1 (Heat shock 70 kDa protein A)
Gene: hsp-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.579

Property	Details
Experiments	23332754
Identification Methods	pull down, x-ray crystallography, isothermal titration calorimetry, molecular sieving
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0044183 - protein folding chaperone
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 961 Ce			1 640
+	Hs
		930977 UN45B_HUMAN (7-943): 0: 837: 30.76		HSP72_HUMAN (2-640): 0: 932: 81.12
+	Hs
		1198774 DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78		Q53FA3_HUMAN (2-640): 0: 960: 80.28
+	Hs
		761494 DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78		HS71L_HUMAN (2-640): 0: 959: 80.60
+	Hs
		600911 DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78		HSP76_HUMAN (2-640): 0: 951: 77.22
+	Hs
		537771 DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78		HSP7C_HUMAN (1-614): 0: 948: 86.32
+	Mm
		989249 PPP5_MOUSE (5-251): 5.58e-41: 160: 18.88		HSP7C_MOUSE (1-614): 0: 948: 86.32
+	Hs
		600777 PPP5_HUMAN (5-240): 6.96e-40: 156: 18.91		HSP76_HUMAN (2-640): 0: 951: 77.22
+	Hs
		516174 DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78		HS71A_HUMAN (1-640): 0: 940: 81.46
+	Hs
		516209 DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78		HS71B_HUMAN (1-640): 0: 940: 81.46
+	Hs
		536809 PPP5_HUMAN (5-240): 6.96e-40: 156: 18.91		HSP7C_HUMAN (1-614): 0: 948: 86.32
+	Hs
		731003 STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57		HS71L_HUMAN (2-640): 0: 959: 80.60
+	At
		103773 OE64M_ARATH (4-126): 7.93e-40: 158: 37.40		HS701_ARATH (2-640): 0: 944: 75.27
+	Hs
		931079 DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78		HSP72_HUMAN (2-640): 0: 932: 81.12
+	At
		653949 OE64C_ARATH (2-126): 9.86e-38: 152: 38.40		HS701_ARATH (2-640): 0: 944: 75.27
+	Hs
		600747 STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57		HSP76_HUMAN (2-640): 0: 951: 77.22
+	Hs
		537770 TTC1_HUMAN (3-159): 3.75e-38: 146: 29.11		HSP7C_HUMAN (1-614): 0: 948: 86.32
+	Hs
		536600 STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57		HSP7C_HUMAN (1-614): 0: 948: 86.32
+	Hs
		516183 STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57		HS71B_HUMAN (1-640): 0: 940: 81.46
+	Dm
		538259 Q9V3E9_DROME (6-164): 1.55e-36: 147: 25.93		HSP7D_DROME (1-613): 0: 932: 84.18
+	Hs
		931078 TTC1_HUMAN (3-159): 3.75e-38: 146: 29.11		HSP72_HUMAN (2-640): 0: 932: 81.12