HitPredict

Interactor 1: IF4H (Q15056)
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein)
Gene: EIF4H

Interactor 2: PMYT1 (Q99640)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)
Gene: PKMYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 499
+	Mm
		591024 TIA1_MOUSE (36-231): 8.23e-34: 127: 13.64		KPCE_MOUSE (8-428): 5.66e-127: 388: 17.05
+	Mm
		424702 TIA1_MOUSE (36-231): 8.23e-34: 127: 13.64		KAPCA_MOUSE (95-401): 3.23e-126: 373: 21.45
+	Mm
		915282 TIA1_MOUSE (36-231): 8.23e-34: 127: 13.64		KAPCB_MOUSE (95-404): 1.98e-126: 373: 21.25
+	Rn
		1224585 PABP1_RAT (33-237): 4.01e-27: 111: 14.49		AKT3_RAT (3-430): 1.89e-129: 386: 19.91
+	Hs
		550110 PABP1_HUMAN (33-237): 3.61e-27: 111: 14.49		KAPCA_HUMAN (95-401): 2.16e-127: 376: 21.45
+	Hs
		605662 PABP4_HUMAN (33-219): 3.99e-24: 102: 13.54		KAPCA_HUMAN (95-401): 2.16e-127: 376: 21.45
+	Hs
		605560 ELAV4_HUMAN (41-123): 2.45e-22: 95.9: 25.88		KAPCA_HUMAN (95-401): 2.16e-127: 376: 21.45
+	Mm
		591036 TIAR_MOUSE (35-179): 3.12e-14: 73.2: 10.88		KPCE_MOUSE (8-428): 5.66e-127: 388: 17.05
+	Hs
		550252 PABP1_HUMAN (33-237): 3.61e-27: 111: 14.49		STK4_HUMAN (80-385): 2.74e-101: 314: 26.52
+	At
		198414 PABP4_ARATH (42-248): 3.22e-25: 105: 13.88		WEE1_ARATH (89-364): 1.33e-33: 134: 33.33
+	Hs
		550502 PABP1_HUMAN (33-237): 3.61e-27: 111: 14.49		KS6B2_HUMAN (102-293): 6.91e-23: 103: 41.50
+	Hs
		908983 PABP4_HUMAN (33-219): 3.99e-24: 102: 13.54		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		908995 RBM39_HUMAN (21-248): 5.32e-22: 96.3: 13.10		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		1097665 RBM39_HUMAN (21-248): 5.32e-22: 96.3: 13.10		STK3_HUMAN (107-376): 6.4e-20: 94.4: 29.29
+	Sc
		692545 NSR1_YEAST (30-140): 9.76e-10: 60.2: 19.47		SWE1_YEAST (100-320): 1.08e-24: 110: 31.38