Interactor 1: NF2L2 (Q60795)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2)
Gene: Nfe2l2

Interactor 2: KEAP1 (Q9Z2X8)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2)
Gene: KEAP1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.767

The method score is based on:

Property Details
Experiments 18358244, 36908855, 19560419, 15143058, 17903176, 16581765, 12145307, 28887507, 30261176, 30126895, 30108253, 18512965, 34229009, 17591699, 17420218, 16785233, 22688683, 16507366, 20173742, 17785452 and 4 others

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Identification Methods affinity chromatography technology, x-ray crystallography, pull down, unspecified method, anti tag coimmunoprecipitation, thermal shift binding, isothermal titration calorimetry, surface plasmon resonance, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription
GO:0016567 - protein ubiquitination
and 2 others

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Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 597
Mm

1 624
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024