Protein: WDR43
WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog)

Gene: WDR43
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q15061

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000785 - chromatin
GO:0000993 - RNA polymerase II complex binding
GO:0001650 - fibrillar center
GO:0003711 - transcription elongation factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1141403

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

7

20

Small-scale

0.962

High

1141398

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

2

20

Small-scale

0.799

High

182300

WDR46
WD repeat-containing protein 46

2

19

High-throughput

0.789

High

1141437

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

2

20

High-throughput

0.789

High

1141422

ANLN
Anillin

2

8

High-throughput

0.754

High

643852

FBRL
rRNA 2'-O-methyltransferase fibrillarin

5

10

High-throughput

0.714

High

228716

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

20

High-throughput

0.691

High

1099679

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

3

High-throughput

0.691

High

302835

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

20

High-throughput

0.675

High

1141433

UTP16
U3 small nucleolar RNA-associated protein NOL7

3

0

High-throughput

0.634

High

1119056

C1D
Nuclear nucleic acid-binding protein C1D

2

2

High-throughput

0.628

High

1141393

WDR75
WD repeat-containing protein 75

2

20

High-throughput

0.628

High

1141412

RBM4
RNA-binding protein 4

2

15

High-throughput

0.628

High

1141417

NOL11
Nucleolar protein 11

2

4

High-throughput

0.628

High

979688

H4
Histone H4

1

13

High-throughput

0.618

High

980784

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

High-throughput

0.618

High

998337

H31
Histone H3.1

1

14

High-throughput

0.618

High

1016875

H33
Histone H3.3

1

14

High-throughput

0.618

High

1141386

EZH2
Histone-lysine N-methyltransferase EZH2

1

19

High-throughput

0.618

High

1141396

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.618

High

1141406

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.618

High

1141411

DDX23
Probable ATP-dependent RNA helicase DDX23

1

14

High-throughput

0.618

High

1141427

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

17

High-throughput

0.618

High

447042

NPM
Nucleophosmin

2

12

High-throughput

0.611

High

1141387

IF16
Gamma-interferon-inducible protein 16

2

13

High-throughput

0.611

High

1141390

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.586

High

345847

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

18

High-throughput

0.584

High

372076

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

978951

RS6
Small ribosomal subunit protein eS6

2

7

High-throughput

0.584

High

1087392

GRSF1
G-rich sequence factor 1

2

20

High-throughput

0.584

High

72774

B0UZZ8
WD repeat-containing protein 46

1

19

High-throughput

0.575

High

396144

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

157399

CTRO
Citron Rho-interacting kinase

1

15

High-throughput

0.553

High

1141389

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.553

High

74495

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

20

High-throughput

0.536

High

288652

NPM3
Nucleoplasmin-3

1

12

High-throughput

0.536

High

691743

MK03
Mitogen-activated protein kinase 3

1

3

High-throughput

0.536

High

1016448

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.536

High

1115664

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

15

High-throughput

0.536

High

1118281

EXOS2
Exosome complex component RRP4

1

4

High-throughput

0.536

High

1141400

ING5
Inhibitor of growth protein 5

1

4

High-throughput

0.536

High

1141409

MPH6
M-phase phosphoprotein 6

1

3

High-throughput

0.536

High

1141410

RBM4B
RNA-binding protein 4B

1

15

High-throughput

0.536

High

1141419

LN28A
Protein lin-28 homolog A

1

6

High-throughput

0.536

High

1141420

EXOS5
Exosome complex component RRP46

1

20

High-throughput

0.536

High

1141421

EXOS3
Exosome complex component RRP40

1

5

High-throughput

0.536

High

1141434

RRP44
Exosome complex exonuclease RRP44

1

6

High-throughput

0.536

High

1141416

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

5

High-throughput

0.521

High

1141428

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

649319

H1T
Histone H1t

1

11

High-throughput

0.489

High

718402

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

961178

FGF12
Fibroblast growth factor 12

1

4

High-throughput

0.489

High

1127385

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.489

High

1141397

CERK1
Ceramide kinase

1

1

High-throughput

0.489

High

1141435

KLH20
Kelch-like protein 20

1

4

High-throughput

0.489

High

134741

SAP18
Histone deacetylase complex subunit SAP18

1

3

High-throughput

0.479

High

140933

NOP56
Nucleolar protein 56

1

15

High-throughput

0.479

High

172835

XPO1
Exportin-1

1

18

High-throughput

0.479

High

190917

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

223058

PRC1
Protein regulator of cytokinesis 1

1

14

High-throughput

0.479

High

247918

NUPR1
Nuclear protein 1

1

6

High-throughput

0.479

High

330983

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

406200

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

487339

PARP1
Poly [ADP-ribose] polymerase 1

1

10

High-throughput

0.479

High

558152

XRCC6
X-ray repair cross-complementing protein 6

1

2

High-throughput

0.479

High

588743

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

695508

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

697124

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

768241

RFA3
Replication protein A 14 kDa subunit

1

9

High-throughput

0.479

High

830769

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

879107

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

15

High-throughput

0.479

High

934636

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.479

High

982677

RS24
Small ribosomal subunit protein eS24

1

5

High-throughput

0.479

High

984780

RL31
Large ribosomal subunit protein eL31

1

4

High-throughput

0.479

High

985673

RL11
Large ribosomal subunit protein uL5

1

6

Small-scale

0.479

High

1032170

EXOSX
Exosome complex component 10

1

9

High-throughput

0.479

High

1035630

KIF23
Kinesin-like protein KIF23

1

19

High-throughput

0.479

High

1045311

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

1097308

CBX3
Chromobox protein homolog 3

1

12

High-throughput

0.479

High

1106889

BIRC3
Baculoviral IAP repeat-containing protein 3

1

10

High-throughput

0.479

High

1137697

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1141388

MIDN
Midnolin

1

1

High-throughput

0.479

High

1141391

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.479

High

1141394

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

1141401

TOPB1
DNA topoisomerase 2-binding protein 1

1

14

High-throughput

0.479

High

1141402

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1141404

CHCH1
Small ribosomal subunit protein mS37

1

3

High-throughput

0.479

High

1141405

DCPS
m7GpppX diphosphatase

1

3

High-throughput

0.479

High

1141407

DDRGK
DDRGK domain-containing protein 1

1

8

High-throughput

0.479

High

1141408

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1141413

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

9

High-throughput

0.479

High

1141414

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

4

High-throughput

0.479

High

1141415

XRN2
5'-3' exoribonuclease 2

1

5

High-throughput

0.479

High

1141418

ECT2
Protein ECT2

1

19

High-throughput

0.479

High

1141423

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

High-throughput

0.479

High

1141425

AATF
Protein AATF

1

7

High-throughput

0.479

High

1141429

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

1141430

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1141431

NUP50
Nuclear pore complex protein Nup50

1

5

High-throughput

0.479

High

1141436

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

429920

JUN
Transcription factor Jun

1

18

High-throughput

0.445

High

584095

FOSL2
Fos-related antigen 2

1

4

High-throughput

0.445

High

601684

HMGA1
High mobility group protein HMG-I/HMG-Y

1

2

High-throughput

0.445

High

756207

MCM7
DNA replication licensing factor MCM7

1

7

Small-scale

0.445

High

770191

RL22
Large ribosomal subunit protein eL22

1

3

High-throughput

0.445

High

904734

MECP2
Methyl-CpG-binding protein 2

1

11

High-throughput

0.445

High

1130260

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

10

High-throughput

0.445

High

1141399

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

15

High-throughput

0.445

High

1141424

GID8
Glucose-induced degradation protein 8 homolog

1

1

High-throughput

0.445

High

1141426

GRHL1
Grainyhead-like protein 1 homolog

1

2

High-throughput

0.445

High

125467

LEG9
Galectin-9

1

7

High-throughput

0.437

High

241727

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.437

High

272196

OBSL1
Obscurin-like protein 1

1

12

High-throughput

0.437

High

318781

RHBT1
Rho-related BTB domain-containing protein 1

1

13

High-throughput

0.437

High

319777

UFL1
E3 UFM1-protein ligase 1

1

5

High-throughput

0.437

High

400857

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

13

High-throughput

0.437

High

1134890

CUL7
Cullin-7

1

11

High-throughput

0.437

High

1140298

KIF14
Kinesin-like protein KIF14

1

15

High-throughput

0.437

High

1141432

HECD1
E3 ubiquitin-protein ligase HECTD1

1

19

High-throughput

0.437

High

1141392

APLF
Aprataxin and PNK-like factor

1

0

High-throughput

0.426

High

1141395

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025