Protein: UTP5
U3 small nucleolar RNA-associated protein 5 (U3 snoRNA-associated protein 5) (U three protein 5) (U3 protein 5 required for transcription) (t-UTP5)

Gene: UTP5
Organism: Saccharomyces cerevisiae S288C
Interactions: 156
UniProt ID: Q04177

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0030490 - maturation of SSU-rRNA
GO:0032040 - small-subunit processome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1045100

UTP15
U3 small nucleolar RNA-associated protein 15

7

16

Small-scale

0.968

High

678450

PWP2
Periodic tryptophan protein 2

3

19

Small-scale

0.827

High

1045106

UTP21
U3 small nucleolar RNA-associated protein 21

2

19

High-throughput

0.793

High

844597

UTP10
U3 small nucleolar RNA-associated protein 10

9

4

Small-scale

0.753

High

1045114

UTP4
U3 small nucleolar RNA-associated protein 4

8

19

Small-scale

0.749

High

806565

UTP9
U3 small nucleolar RNA-associated protein 9

5

1

High-throughput

0.719

High

919162

UTP8
U3 small nucleolar RNA-associated protein 8

5

1

Small-scale

0.717

High

798299

ENP1
Essential nuclear protein 1

5

2

Small-scale

0.699

High

1045098

UTP5
U3 small nucleolar RNA-associated protein 5

1

16

High-throughput

0.698

High

1039842

UTP17
NET1-associated nuclear protein 1

4

20

Small-scale

0.691

High

1045099

DHR1
Probable ATP-dependent RNA helicase DHR1

4

11

Small-scale

0.676

High

1045111

NOC4
Nucleolar complex protein 4

4

4

Small-scale

0.676

High

865161

MPP10
U3 small nucleolar RNA-associated protein MPP10

3

2

Small-scale

0.656

High

923978

CSL4
Exosome complex component CSL4

3

2

Small-scale

0.640

High

1045134

NOP58
Nucleolar protein 58

3

13

Small-scale

0.640

High

747042

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

7

High-throughput

0.637

High

918814

UTP22
U3 small nucleolar RNA-associated protein 22

2

3

High-throughput

0.637

High

1045105

UTP13
U3 small nucleolar RNA-associated protein 13

1

19

High-throughput

0.618

High

1045127

UTP12
U3 small nucleolar RNA-associated protein 12

1

15

High-throughput

0.618

High

817623

UTP7
U3 small nucleolar RNA-associated protein 7

2

17

High-throughput

0.614

High

818334

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

1

High-throughput

0.614

High

825075

RRT14
Regulator of rDNA transcription protein 14

2

1

High-throughput

0.614

High

826205

FAF1
Protein FAF1

2

1

Small-scale

0.611

High

1045107

SGD1
Suppressor of glycerol defect protein 1

2

5

High-throughput

0.611

High

677549

KRR1
KRR1 small subunit processome component

2

1

High-throughput

0.584

High

823378

UTP18
U3 small nucleolar RNA-associated protein 18

2

4

Small-scale

0.584

High

864509

MTR4
ATP-dependent RNA helicase DOB1

2

16

Small-scale

0.584

High

924622

NAT10
RNA cytidine acetyltransferase

2

2

High-throughput

0.584

High

1045101

UTP14
U3 small nucleolar RNA-associated protein 14

2

2

High-throughput

0.584

High

1045125

RRP6
Exosome complex exonuclease RRP6

2

6

High-throughput

0.584

High

923121

BRE5
UBP3-associated protein BRE5

2

5

High-throughput

0.567

High

564679

STE12
Protein STE12

1

1

High-throughput

0.541

High

779156

DHR2
Probable ATP-dependent RNA helicase DHR2

1

10

High-throughput

0.541

High

1045130

UTP23
rRNA-processing protein UTP23

1

2

High-throughput

0.541

High

503227

RS22A
Small ribosomal subunit protein uS8A

2

3

High-throughput

0.533

High

918612

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

740754

SRP40
Suppressor protein SRP40

1

2

High-throughput

0.515

High

789842

YC16
UPF0743 protein YCR087C-A

1

3

High-throughput

0.515

High

819712

SSB2
Ribosome-associated molecular chaperone SSB2

2

14

High-throughput

0.504

High

488630

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

1

High-throughput

0.489

High

796179

OLA1
Obg-like ATPase 1

1

5

High-throughput

0.489

High

868443

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

4

High-throughput

0.489

High

921103

PRS10
26S proteasome subunit RPT4

1

14

High-throughput

0.489

High

922685

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

High-throughput

0.489

High

1028026

ACAC
Acetyl-CoA carboxylase

1

8

High-throughput

0.489

High

1043449

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

2

High-throughput

0.489

High

436159

RS13
Small ribosomal subunit protein uS15

1

4

High-throughput

0.479

High

442100

RS14A
Small ribosomal subunit protein uS11A

1

4

High-throughput

0.479

High

512637

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.479

High

585362

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

9

High-throughput

0.479

High

632732

DBP4
ATP-dependent RNA helicase HCA4

1

13

High-throughput

0.479

High

672939

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.479

High

673220

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

674823

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

689647

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

753574

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

754324

DCA13
Protein SOF1

1

18

High-throughput

0.479

High

758401

UTP11
U3 small nucleolar RNA-associated protein 11

1

1

High-throughput

0.479

High

763619

UTP20
U3 small nucleolar RNA-associated protein 20

1

1

High-throughput

0.479

High

782098

RL1D1
Ribosome biogenesis protein UTP30

1

4

High-throughput

0.479

High

802899

DBP8
ATP-dependent RNA helicase DBP8

1

13

High-throughput

0.479

High

804743

RRP4
Exosome complex component RRP4

1

9

High-throughput

0.479

High

804951

LRP1
Exosome complex protein LRP1

1

1

High-throughput

0.479

High

808301

RRP8
25S rRNA

1

3

High-throughput

0.479

High

825554

UTP25
U3 small nucleolar RNA-associated protein 25

1

1

High-throughput

0.479

High

836200

DIM1
Dimethyladenosine transferase

1

1

High-throughput

0.479

High

852595

ROK1
ATP-dependent RNA helicase ROK1

1

10

High-throughput

0.479

High

863130

RRP41
Exosome complex component SKI6

1

19

High-throughput

0.479

High

864954

NOP9
Nucleolar protein 9

1

1

Small-scale

0.479

High

871047

NOL10
Ribosome biogenesis protein ENP2

1

2

High-throughput

0.479

High

871118

MTR3
Exosome complex component MTR3

1

1

High-throughput

0.479

High

918886

RRP46
Exosome complex component RRP46

1

17

High-throughput

0.479

High

918979

PESC
Pescadillo homolog

1

2

High-throughput

0.479

High

923246

ESF2
Pre-rRNA-processing protein ESF2

1

3

High-throughput

0.479

High

925189

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

2

High-throughput

0.479

High

1036400

UTP6
U3 small nucleolar RNA-associated protein 6

1

3

High-throughput

0.479

High

1042223

TOM1
E3 ubiquitin-protein ligase TOM1

1

9

High-throughput

0.479

High

1045102

RRP5
rRNA biogenesis protein RRP5

1

16

High-throughput

0.479

High

1045103

FCF1
rRNA-processing protein FCF1

1

2

High-throughput

0.479

High

1045104

RRP45
Exosome complex component RRP45

1

11

High-throughput

0.479

High

1045108

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

1

High-throughput

0.479

High

1045109

ESF1
Pre-rRNA-processing protein ESF1

1

1

High-throughput

0.479

High

1045110

RRP9
Ribosomal RNA-processing protein 9

1

17

High-throughput

0.479

High

1045112

BFR2
Protein BFR2

1

4

High-throughput

0.479

High

1045116

RCL1
rRNA processing protein RCL1

1

1

High-throughput

0.479

High

1045117

RRP44
Exosome complex exonuclease DIS3

1

6

High-throughput

0.479

High

1045118

RRP40
Exosome complex component RRP40

1

4

High-throughput

0.479

High

1045120

UTP16
U3 small nucleolar RNA-associated protein 16

1

1

High-throughput

0.479

High

1045122

BMS1
Ribosome biogenesis protein BMS1

1

4

High-throughput

0.479

High

1045123

FCF2
rRNA-processing protein FCF2

1

2

High-throughput

0.479

High

1045124

SAS10
Something about silencing protein 10

1

2

High-throughput

0.479

High

1045128

RRP42
Exosome complex component RRP42

1

11

High-throughput

0.479

High

1045131

DBP10
ATP-dependent RNA helicase DBP10

1

15

High-throughput

0.479

High

1045132

NOP56
Nucleolar protein 56

1

13

High-throughput

0.479

High

1045133

RRP36
rRNA biogenesis protein RRP36

1

1

High-throughput

0.479

High

1045136

RRP12
Ribosomal RNA-processing protein 12

1

3

High-throughput

0.479

High

1045137

EFG1P
rRNA-processing protein EFG1

1

1

High-throughput

0.479

High

1045140

NOP14
Nucleolar complex protein 14

1

2

High-throughput

0.479

High

1045141

PNO1
Pre-rRNA-processing protein PNO1

1

1

High-throughput

0.479

High

1045126

YRA1
RNA annealing protein YRA1

1

8

High-throughput

0.470

High

804654

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.458

High

758332

HSL1
Probable serine/threonine-protein kinase HSL1

1

3

High-throughput

0.457

High

874261

CLA4
Serine/threonine-protein kinase CLA4

1

1

Small-scale

0.457

High

1042992

STE20
Serine/threonine-protein kinase STE20

1

3

Small-scale

0.457

High

367807

ENO1
Enolase 1

1

3

High-throughput

0.457

High

405138

LEU3
3-isopropylmalate dehydrogenase

1

6

High-throughput

0.457

High

408345

GAL1
Galactokinase

1

1

High-throughput

0.457

High

408587

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

1

High-throughput

0.457

High

590714

HSP26
Heat shock protein 26

1

4

High-throughput

0.457

High

644836

CLH
Clathrin heavy chain

1

5

High-throughput

0.457

High

701565

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

3

High-throughput

0.457

High

734199

EF2
Elongation factor 2

1

6

High-throughput

0.457

High

779101

EF1G2
Elongation factor 1-gamma 2

1

3

High-throughput

0.457

High

926280

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

High-throughput

0.457

High

1044452

RUVB1
RuvB-like protein 1

1

5

High-throughput

0.457

High

1045129

HSP42
Heat shock protein 42

1

4

High-throughput

0.457

High

383884

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

435344

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.437

High

708092

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

709966

BMH1
Protein BMH1

1

4

High-throughput

0.437

High

747565

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

748031

SMY2
Protein SMY2

1

2

High-throughput

0.437

High

792233

GBLP
Small ribosomal subunit protein RACK1

1

18

High-throughput

0.437

High

795198

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

804122

RPP1
Ribonuclease P/MRP protein subunit RPP1

1

1

High-throughput

0.437

High

811492

XDJ1
DnaJ protein homolog XDJ1

1

9

High-throughput

0.437

High

812627

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

826807

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.437

High

918445

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.437

High

925028

APJ1
J domain-containing protein APJ1

1

13

High-throughput

0.437

High

1033550

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

1045115

CMS1
Protein CMS1

1

1

High-throughput

0.437

High

1045119

SGO1
Shugoshin

1

1

High-throughput

0.437

High

1045121

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

1045138

RS22B
Small ribosomal subunit protein uS8B

1

3

High-throughput

0.437

High

1045139

HUB1
Ubiquitin-like modifier HUB1

1

1

Small-scale

0.437

High

782437

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

792572

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.417

High

546164

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.407

High

580015

HSC82
ATP-dependent molecular chaperone HSC82

1

12

High-throughput

0.407

High

597266

BIP
Endoplasmic reticulum chaperone BiP

1

11

High-throughput

0.407

High

742330

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.407

High

752694

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

823646

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.407

High

1045113

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

10

High-throughput

0.407

High

455521

PMM
Phosphomannomutase

1

0

High-throughput

0.279

Low

865613

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.279

Low

1044047

RIFK
Riboflavin kinase

1

0

High-throughput

0.265

Low

439423

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.261

Low

454130

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.261

Low

470041

GAL7
Galactose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

471433

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.261

Low

558859

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

922949

MPP6
M-phase phosphoprotein 6 homolog

1

0

High-throughput

0.249

Low

1045135

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025