HitPredict

Interactor 1: EEA1 (Q15075)
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)
Gene: EEA1

Interactor 2: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1411 Hs			1 1140
+	Hs
		776817 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MYH11_HUMAN (417-1140): 2.46e-43: 174: 15.36
+	Hs
		772813 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MYH9_HUMAN (372-1140): 3.39e-40: 164: 13.23
+	Hs
		563056 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MYH8_HUMAN (417-1139): 1.14e-39: 162: 11.64
+	Hs
		1142035 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MYH15_HUMAN (438-1116): 2.16e-15: 83.9: 13.56
+	Hs
		883904 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		CENPF_HUMAN (101-707): 3.11e-10: 67: 13.08
+	Hs
		1226255 CP250_HUMAN (311-1410): 7.38e-38: 158: 12.73		CP135_HUMAN (1-1140): 1.37e-87: 309: 100.00
+	Hs
		773204 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		CP135_HUMAN (1-1140): 1.37e-87: 309: 100.00
+	Hs
		772991 CP250_HUMAN (311-1410): 7.38e-38: 158: 12.73		MYH9_HUMAN (372-1140): 3.39e-40: 164: 13.23
+	Hs
		773112 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		MYH11_HUMAN (417-1140): 2.46e-43: 174: 15.36
+	Hs
		1191475 CP250_HUMAN (311-1410): 7.38e-38: 158: 12.73		GRDN_HUMAN (310-1140): 9.76e-33: 140: 12.47
+	Hs
		772645 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		MYH9_HUMAN (372-1140): 3.39e-40: 164: 13.23
+	Hs
		773110 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		MYH10_HUMAN (401-1140): 2.25e-39: 162: 13.52
+	Hs
		556902 MYH7_HUMAN (1-591): 3.62e-26: 119: 12.80		MYH9_HUMAN (372-1140): 3.39e-40: 164: 13.23
+	Hs
		556973 MYH7_HUMAN (1-591): 3.62e-26: 119: 12.80		MYH4_HUMAN (428-1140): 7.05e-38: 157: 13.72
+	Hs
		556892 MYH7_HUMAN (1-591): 3.62e-26: 119: 12.80		MYH7_HUMAN (470-1128): 3e-36: 152: 14.22
+	Rn
		386940 MYH6_RAT (1-601): 1.02e-25: 118: 12.75		MYH6_RAT (470-1128): 1.74e-34: 146: 13.93
+	Hs
		562992 MYH6_HUMAN (1-601): 3.27e-26: 119: 12.75		MYH6_HUMAN (456-1139): 3.79e-33: 141: 12.59
+	Mm
		98073 MYH9_MOUSE (671-1410): 1.33e-30: 134: 12.58		DESP_MOUSE (212-1059): 2.2e-26: 120: 14.43
+	Zm
		5583 A0A1D6DZK4_MAIZE (717-1410): 1.1e-27: 124: 13.08		A0A1D6DZK4_MAIZE (1-641): 2.39e-20: 100: 10.51
+	Hs
		535921 MYH6_HUMAN (1-601): 3.27e-26: 119: 12.75		MYH3_HUMAN (1-555): 9.5e-19: 94.8: 11.81