Interactor 1: I17RA (Q60943)
Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CD antigen CD217)
Gene: Il17ra

Interactor 2: IL17 (Q62386)
Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Gene: Il17a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21993849
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL17~IL17R_fnIII_D1, IL17~IL17R_fnIII_D2
Common GO terms GO:0006954 - inflammatory response
GO:0032747 - positive regulation of interleukin-23 production
GO:0032755 - positive regulation of interleukin-6 production
GO:0038173 - interleukin-17A-mediated signaling pathway
GO:0045087 - innate immune response
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 864
Mm

1 158
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024