HitPredict

Interactor 1: EEA1 (Q15075)
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)
Gene: EEA1

Interactor 2: TRAIP (Q9BWF2)
E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (RING finger protein 206) (TRAF-interacting protein)
Gene: TRAIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1411 Hs			1 469
+	Hs
		1141990 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		CING_HUMAN (37-297): 1.7e-37: 148: 12.59
+	Hs
		1141652 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MTUS2_HUMAN (13-357): 3.39e-25: 111: 14.94
+	Hs
		1142045 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MRCKB_HUMAN (26-379): 4.51e-16: 83.4: 13.02
+	Hs
		1081695 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		CGNL1_HUMAN (65-280): 2.2e-10: 65.2: 10.66
+	Hs
		776817 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MYH11_HUMAN (29-307): 1.75e-09: 62.5: 17.07
+	Hs
		772813 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MYH9_HUMAN (41-307): 2.25e-09: 62.1: 14.47
+	Hs
		563056 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MYH8_HUMAN (4-378): 8.48e-09: 60.3: 9.49
+	Hs
		772991 CP250_HUMAN (311-1410): 7.38e-38: 158: 12.73		MYH9_HUMAN (41-307): 2.25e-09: 62.1: 14.47
+	Hs
		773214 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		MYH14_HUMAN (75-300): 3.35e-19: 93.3: 15.66
+	Mm
		98073 MYH9_MOUSE (671-1410): 1.33e-30: 134: 12.58		DESP_MOUSE (53-372): 7.87e-10: 63.8: 12.77
+	Hs
		773110 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		MYH10_HUMAN (77-300): 1.02e-09: 63.3: 14.40
+	Hs
		773112 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		MYH11_HUMAN (29-307): 1.75e-09: 62.5: 17.07
+	Hs
		772645 MYH10_HUMAN (819-1407): 6.05e-28: 125: 13.28		MYH9_HUMAN (41-307): 2.25e-09: 62.1: 14.47
+	Hs
		535921 MYH6_HUMAN (1-601): 3.27e-26: 119: 12.75		MYH3_HUMAN (39-275): 5.75e-11: 67.1: 15.10
+	Hs
		556902 MYH7_HUMAN (1-591): 3.62e-26: 119: 12.80		MYH9_HUMAN (41-307): 2.25e-09: 62.1: 14.47
+	Hs
		556973 MYH7_HUMAN (1-591): 3.62e-26: 119: 12.80		MYH4_HUMAN (17-380): 4.59e-09: 61.1: 11.61
+	Rn
		386940 MYH6_RAT (1-601): 1.02e-25: 118: 12.75		MYH6_RAT (31-378): 2.71e-09: 61.8: 12.67
+	Hs
		556892 MYH7_HUMAN (1-591): 3.62e-26: 119: 12.80		MYH7_HUMAN (18-349): 7.91e-09: 60.3: 13.47
+	Hs
		562992 MYH6_HUMAN (1-601): 3.27e-26: 119: 12.75		MYH6_HUMAN (49-290): 9.51e-09: 60.2: 13.77
+	Hs
		563081 MYH8_HUMAN (1-562): 1.23e-25: 117: 11.49		MYH4_HUMAN (17-380): 4.59e-09: 61.1: 11.61