HitPredict

Interactor 1: ATRX (Q61687)
Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (HP1 alpha-interacting protein) (HP1-BP38 protein) (Heterochromatin protein 2) (X-linked nuclear protein)
Gene: ATRX

Interactor 2: MCM7 (Q61881)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog)
Gene: MCM7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34162889
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2476 Mm			1 719
+	Hs
		708832 ATRX_HUMAN (1-2476): 0: 1016: 80.87		MCM7_HUMAN (1-719): 0: 787: 92.77
+	Mm
		956191 ATRX_MOUSE (1-2476): 0: 1129: 100.00		MCM2_MOUSE (8-718): 0: 661: 27.06
+	Mm
		956201 ATRX_MOUSE (1-2476): 0: 1129: 100.00		MCM6_MOUSE (7-714): 0: 637: 27.57
+	Hs
		802405 ATRX_HUMAN (1-2476): 0: 1016: 80.87		MCM2_HUMAN (8-718): 0: 664: 27.06
+	Hs
		708393 ATRX_HUMAN (1-2476): 0: 1016: 80.87		MCM4_HUMAN (7-700): 0: 647: 31.75
+	Hs
		802437 ATRX_HUMAN (1-2476): 0: 1016: 80.87		MCM6_HUMAN (1-717): 0: 646: 27.77
+	Sc
		667853 ISW1_YEAST (1992-2212): 3.86e-57: 220: 28.07		MCM5_YEAST (4-716): 0: 641: 27.34
+	Hs
		708880 CHD3_HUMAN (166-377): 2.11e-11: 72.3: 13.87		MCM7_HUMAN (1-719): 0: 787: 92.77
+	Hs
		708618 CHD3_HUMAN (166-377): 2.11e-11: 72.3: 13.87		MCM5_HUMAN (6-716): 0: 694: 27.61
+	Hs
		832409 CHD3_HUMAN (166-377): 2.11e-11: 72.3: 13.87		MCM2_HUMAN (8-718): 0: 664: 27.06
+	Hs
		1055555 CHD4_HUMAN (166-378): 7.45e-13: 76.9: 14.29		MCM6_HUMAN (1-717): 0: 646: 27.77