HitPredict

Interactor 1: ESPN (Q63618)
Espin (Ectoplasmic specialization protein)
Gene: ESPN

Interactor 2: BAIP2 (Q6GMN2)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase substrate protein p53)
Gene: Baiap2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	12598619
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0043197 - dendritic spine GO:0051017 - actin filament bundle assembly
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 837 Rn			1 535
+	Hs
		69745 ESPN_HUMAN (1-837): 5.5e-135: 424: 76.32		BAIP2_HUMAN (1-529): 6.96e-143: 424: 94.52
+	Hs
		69743 ESPN_HUMAN (1-837): 5.5e-135: 424: 76.32		BI2L1_HUMAN (3-534): 6.5e-120: 364: 39.31
+	Hs
		862132 DAPK1_HUMAN (2-267): 1.86e-70: 255: 26.69		BAIP2_HUMAN (1-529): 6.96e-143: 424: 94.52
+	Hs
		862037 DAPK1_HUMAN (2-267): 1.86e-70: 255: 26.69		SPTN1_HUMAN (6-443): 2.52e-50: 188: 14.29
+	Hs
		1021717 ANR50_HUMAN (151-501): 1.27e-44: 176: 17.96		MYO1E_HUMAN (50-436): 1.87e-46: 176: 11.90
+	Mm
		1142988 ANS1B_MOUSE (94-310): 1.26e-21: 103: 36.07		PACN1_MOUSE (13-436): 4.09e-56: 196: 13.76
+	Mm
		82740 ANK3_MOUSE (1-89): 3.08e-17: 89.3: 21.35		B9EKJ1_MOUSE (6-443): 1.55e-51: 192: 14.29
+	Mm
		561172 ANK2_MOUSE (1-89): 5.82e-17: 88.5: 23.60		SPTN1_MOUSE (6-443): 1.9e-51: 191: 14.29
+	Hs
		965102 ANK2_HUMAN (1-89): 2.35e-17: 89.7: 23.60		SPTN1_HUMAN (6-443): 2.52e-50: 188: 14.29
+	Hs
		1021399 ANK3_HUMAN (1-89): 2.76e-16: 86.2: 22.47		SPTN1_HUMAN (6-443): 2.52e-50: 188: 14.29
+	Hs
		1021703 Q9H4D1_HUMAN (134-348): 5.81e-09: 62: 28.24		MYO1E_HUMAN (50-436): 1.87e-46: 176: 11.90
+	Hs
		883497 RIPK4_HUMAN (134-348): 7.01e-09: 61.6: 28.24		MYO1E_HUMAN (50-436): 1.87e-46: 176: 11.90
+	Hs
		257713 ANR17_HUMAN (1-193): 2.52e-37: 153: 28.21		ITSN2_HUMAN (237-434): 3.64e-10: 65: 15.00
+	Hs
		1078859 MIB1_HUMAN (159-354): 1.81e-22: 105: 21.32		ITSN1_HUMAN (357-458): 8.72e-10: 64: 18.63
+	Mm
		1206702 ANS1B_MOUSE (94-310): 1.26e-21: 103: 36.07		ITSN1_MOUSE (357-458): 6.79e-09: 60.9: 18.63