HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: ARHGH (Q96PE2)
Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)
Gene: ARHGEF17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Hs			1 2063
+	Hs
		1146697 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74
+	Hs
		1146534 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		DNMBP_HUMAN (539-1741): 1.41e-93: 338: 15.90
+	Hs
		1146905 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ITSN2_HUMAN (684-1531): 1.73e-91: 333: 15.69
+	Hs
		1146952 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		PKHG1_HUMAN (1004-1748): 4.12e-92: 332: 14.88
+	Hs
		1138646 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ARHGG_HUMAN (853-1410): 1.52e-82: 289: 15.87
+	Hs
		1066028 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ARHG6_HUMAN (1070-1381): 1.5e-70: 256: 21.27
+	Hs
		548721 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		VAV_HUMAN (1000-1350): 1.81e-67: 248: 21.63
+	Hs
		1288351 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		ITSN2_HUMAN (684-1531): 1.73e-91: 333: 15.69
+	Hs
		61736 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		A6H8W8_HUMAN (684-1531): 7.36e-91: 330: 15.69
+	Hs
		921674 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74
+	Hs
		1288311 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		ECT2_HUMAN (984-1451): 4.6e-72: 263: 20.70
+	Mm
		1141825 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		ARHG2_MOUSE (858-1740): 3.4e-105: 364: 15.48
+	Mm
		70591 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		B2RR82_MOUSE (578-1531): 4.72e-90: 328: 13.89
+	Hs
		1254029 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		PREX1_HUMAN (1039-1431): 1.2e-74: 278: 23.91
+	Hs
		224710 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		KALRN_HUMAN (1043-1788): 7.56e-71: 267: 12.89
+	Hs
		921728 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		ECT2_HUMAN (984-1451): 4.6e-72: 263: 20.70
+	Hs
		921052 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		ECT2_HUMAN (984-1451): 4.6e-72: 263: 20.70
+	Hs
		1333738 GBB4_HUMAN (165-516): 4.49e-42: 156: 16.07		ECT2_HUMAN (984-1451): 4.6e-72: 263: 20.70
+	Mm
		654987 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		VAV_MOUSE (991-1350): 1.21e-69: 255: 21.89
+	Mm
		1207616 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		ARHG6_MOUSE (1070-1380): 6.44e-69: 251: 20.38