HitPredict

Interactor 1: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26496610, 31586073, 33961781, 36526897
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1117 Hs			1 1124
+	Hs
		1129141 CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		993298 ACTN3_HUMAN (1009-1115): 7.86e-51: 196: 40.74		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		521622 ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		725703 ACTN2_HUMAN (1009-1115): 3.7e-48: 188: 41.67		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		211670 ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		725034 MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		725252 MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		728519 MYH11_HUMAN (342-1028): 7.19e-25: 114: 9.72		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		502927 MYH3_HUMAN (372-1035): 6.82e-24: 111: 10.16		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (1012-1115): 7.3e-16: 85.5: 47.62		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		1303384 MYSN_DROME (348-1092): 6.68e-23: 108: 12.32		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84