HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: PECA1 (P16284)
Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31)
Gene: PECAM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10858437
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045121 - membrane raft
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 738
+	Hs
		522751 SRC_HUMAN (1-537): 0: 598: 68.21		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		433242 YES_HUMAN (1-537): 0: 591: 71.61		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		411584 LCK_HUMAN (40-535): 0: 551: 57.60		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		442774 HCK_HUMAN (1-535): 0: 548: 56.64		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		433561 LYN_HUMAN (1-535): 0: 535: 54.48		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		557441 ABL2_HUMAN (7-537): 2.06e-170: 515: 38.09		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		434019 LYN_HUMAN (1-535): 0: 535: 54.48		ROBO2_HUMAN (11-737): 1.39e-82: 288: 12.20
+	Hs
		297881 FYN_HUMAN (1-537): 0: 643: 100.00		NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71
+	Hs
		433804 LYN_HUMAN (1-535): 0: 535: 54.48		SDK2_HUMAN (247-738): 8.87e-51: 194: 12.69
+	Mm
		639452 LYN_MOUSE (1-535): 0: 535: 53.92		FCRL5_MOUSE (230-631): 2.04e-45: 173: 17.99
+	Hs
		433569 LYN_HUMAN (1-535): 0: 535: 54.48		CD22_HUMAN (282-633): 8.62e-41: 162: 15.93
+	Hs
		433249 YES_HUMAN (1-537): 0: 591: 71.61		VCAM1_HUMAN (28-407): 7.14e-17: 86.9: 19.75
+	Hs
		434111 LYN_HUMAN (1-535): 0: 535: 54.48		ROBO1_HUMAN (405-725): 5.45e-33: 139: 11.87
+	Hs
		297880 ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56		NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71
+	Hs
		433742 LYN_HUMAN (1-535): 0: 535: 54.48		PTK7_HUMAN (8-235): 3.28e-27: 120: 12.45
+	Hs
		255429 LCK_HUMAN (40-535): 0: 551: 57.60		OBSL1_HUMAN (72-603): 1.4e-14: 80.3: 15.01