HitPredict

Interactor 1: Q6GX22 (Q6GX22)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: Q6GX22

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19690564
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 147
+	Hs
		1356055 TRIM1_HUMAN (1-685): 0: 543: 95.52		UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00
+	Hs
		849480 TRIM1_HUMAN (1-685): 0: 543: 95.52		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919896 TRIM1_HUMAN (1-685): 0: 543: 95.52		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895945 TRIM1_HUMAN (1-685): 0: 543: 95.52		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		1297378 TRIM1_HUMAN (1-685): 0: 543: 95.52		UB2E2_HUMAN (4-146): 3.5e-75: 224: 64.34
+	Hs
		1282363 TRIM1_HUMAN (1-685): 0: 543: 95.52		UB2E3_HUMAN (4-146): 1.24e-74: 223: 64.34
+	Hs
		896464 Q6GX22_HUMAN (1-685): 0: 558: 100.00		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		175730 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00
+	Hs
		851905 TRIM1_HUMAN (1-685): 0: 543: 95.52		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		175653 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		175664 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		175658 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		896562 TRIM1_HUMAN (1-685): 0: 543: 95.52		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		175710 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UB2E2_HUMAN (4-146): 3.5e-75: 224: 64.34
+	Hs
		175703 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UB2E3_HUMAN (4-146): 1.24e-74: 223: 64.34
+	Hs
		175654 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		175660 TRI18_HUMAN (1-667): 6.81e-176: 518: 76.01		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		849330 TRI25_HUMAN (4-656): 8.12e-105: 334: 22.46		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919872 TRI36_HUMAN (1-668): 6.86e-104: 334: 22.78		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895794 TRI25_HUMAN (4-656): 8.12e-105: 334: 22.46		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84