HitPredict

Interactor 1: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Interactor 2: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 356
+	Hs
		978300 RHOB_HUMAN (6-191): 9.7e-86: 252: 40.93		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		988702 RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		581284 RAC2_HUMAN (2-191): 3.12e-74: 223: 38.07		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		953669 RAC3_HUMAN (2-171): 1.04e-73: 221: 41.81		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1015780 RHOG_HUMAN (2-191): 6.18e-73: 220: 37.06		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		955584 CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		962473 RHOA_HUMAN (6-191): 3.36e-72: 218: 38.86		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1025810 RHOH_HUMAN (1-191): 4.41e-96: 278: 100.00		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		466205 RHOC_HUMAN (6-185): 8.96e-86: 252: 42.25		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		977940 RHOB_HUMAN (6-191): 9.7e-86: 252: 40.93		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		988283 RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		580993 RAC2_HUMAN (2-191): 3.12e-74: 223: 38.07		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		955737 CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61		BORG2_HUMAN (2-229): 1.36e-56: 186: 24.21
+	Hs
		953395 RAC3_HUMAN (2-171): 1.04e-73: 221: 41.81		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		1015370 RHOG_HUMAN (2-191): 6.18e-73: 220: 37.06		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		955065 CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		961957 RHOA_HUMAN (6-191): 3.36e-72: 218: 38.86		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		158724 CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86
+	Hs
		158721 RHOQ_HUMAN (5-190): 9.56e-72: 217: 39.49		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86
+	Hs
		955300 CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61		BORG3_HUMAN (1-56): 7.62e-15: 72.7: 60.71