HitPredict

Interactor 1: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Interactor 2: NLGN2 (Q8NFZ4)
Neuroligin-2
Gene: NLGN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	9278515
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0035418 - protein localization to synapse GO:0098609 - cell-cell adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 835
+	Hs
		1152421 DLG2_HUMAN (1-870): 0: 732: 100.00		NLGN3_HUMAN (1-835): 0: 797: 60.05
+	Hs
		1152413 DLG2_HUMAN (1-870): 0: 732: 100.00		NLGN1_HUMAN (16-835): 0: 785: 60.46
+	Rn
		1224303 DLG2_RAT (1-870): 0: 718: 94.94		NLGN2_RAT (1-835): 0: 794: 98.33
+	Rn
		1224273 DLG2_RAT (1-870): 0: 718: 94.94		NLGN1_RAT (31-835): 0: 776: 62.95
+	Dm
		723790 DLG1_DROME (26-870): 1.77e-155: 482: 47.61		Q7KT70_DROME (12-634): 1.21e-155: 481: 28.66
+	Mm
		1223630 DLG4_MOUSE (13-446): 2.95e-30: 129: 16.52		NLGN3_MOUSE (1-835): 0: 801: 62.50
+	Hs
		1006111 DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52		NLGN3_HUMAN (1-835): 0: 797: 60.05
+	Mm
		1223559 DLG4_MOUSE (13-446): 2.95e-30: 129: 16.52		NLGN2_MOUSE (1-835): 0: 797: 98.21
+	Hs
		1368725 DLG3_HUMAN (11-444): 5.43e-30: 129: 15.08		NLGN3_HUMAN (1-835): 0: 797: 60.05
+	Mm
		59318 DLG4_MOUSE (13-446): 2.95e-30: 129: 16.52		A2AGI2_MOUSE (1-835): 0: 797: 60.71
+	Rn
		723885 DLG4_RAT (13-446): 5.09e-30: 129: 16.52		NLGN2_RAT (1-835): 0: 794: 98.33
+	Hs
		1006086 DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52		NLGN2_HUMAN (1-835): 0: 789: 100.00
+	Hs
		1339603 DLG3_HUMAN (11-444): 5.43e-30: 129: 15.08		NLGN2_HUMAN (1-835): 0: 789: 100.00
+	Hs
		1006084 DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52		NLGN1_HUMAN (16-835): 0: 785: 60.46
+	Hs
		1006083 DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52		NLGNX_HUMAN (37-835): 0: 784: 62.47
+	Hs
		1324499 DLG3_HUMAN (11-444): 5.43e-30: 129: 15.08		NLGN1_HUMAN (16-835): 0: 785: 60.46
+	Rn
		723884 DLG4_RAT (13-446): 5.09e-30: 129: 16.52		NLGN1_RAT (31-835): 0: 776: 62.95
+	Rn
		1224299 DLG3_RAT (270-492): 1.6e-12: 73.7: 16.59		NLGN2_RAT (1-835): 0: 794: 98.33
+	Rn
		1224271 DLG3_RAT (270-492): 1.6e-12: 73.7: 16.59		NLGN1_RAT (31-835): 0: 776: 62.95