HitPredict

Interactor 1: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0017124 - SH3 domain binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 474
+	Hs
		1399541 MIA2_HUMAN (4-469): 1.28e-30: 128: 12.65		CTGE2_HUMAN (28-469): 3.04e-27: 117: 12.05
+	Hs
		1290894 TAXB1_HUMAN (59-365): 6.04e-28: 119: 20.46		TAXB1_HUMAN (59-365): 6.04e-28: 119: 20.46
+	Hs
		1291024 TAXB1_HUMAN (59-365): 6.04e-28: 119: 20.46		MRCKB_HUMAN (23-351): 3.72e-20: 96.2: 14.57
+	Rn
		1274668 MRCKB_RAT (23-351): 1.67e-21: 100: 15.25		MRCKB_RAT (23-351): 1.67e-21: 100: 15.25
+	Rn
		700319 DCTN1_RAT (7-361): 1.3e-21: 100: 13.17		DCTN1_RAT (7-361): 1.3e-21: 100: 13.17
+	Rn
		236530 MRCKB_RAT (23-351): 1.67e-21: 100: 15.25		MRCKA_RAT (42-413): 1.73e-13: 75.4: 14.60
+	Hs
		1217577 MRCKB_HUMAN (23-351): 3.72e-20: 96.2: 14.57		MRCKA_HUMAN (44-468): 6.79e-12: 70: 13.40
+	Hs
		773040 MYO5C_HUMAN (38-376): 2.2e-18: 90.8: 14.25		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		1365629 MRCKB_HUMAN (23-351): 3.72e-20: 96.2: 14.57		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		1365601 MYO5C_HUMAN (38-376): 2.2e-18: 90.8: 14.25		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Rn
		236526 MRCKA_RAT (42-413): 1.73e-13: 75.4: 14.60		MRCKA_RAT (42-413): 1.73e-13: 75.4: 14.60
+	Hs
		772644 MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		772645 MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32		MYH10_HUMAN (3-329): 8.29e-11: 66.9: 13.46
+	Hs
		556902 MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32		MYH7_HUMAN (36-399): 1.4e-10: 66.2: 10.22
+	Hs
		772647 MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32		MYH11_HUMAN (54-323): 1.65e-09: 62.6: 17.07
+	Hs
		772814 MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32		PLEC_HUMAN (67-346): 2.75e-09: 61.9: 11.79
+	Hs
		157020 MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32		CTRO_HUMAN (50-380): 3.18e-09: 61.6: 12.47