HitPredict

Interactor 1: M9PFV2 (M9PFV2)
Myosin phosphatase targeting subunit 75D, isoform B
Gene: MYPT-75D

Interactor 2: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15269282
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0017018 - myosin phosphatase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 635 Dm			1 302
+	Dm
		115663 M9PFV2_DROME (1-635): 5.24e-126: 387: 100.00		PP1B_DROME (1-302): 0: 530: 85.48
+	Dm
		819281 Q8SY34_DROME (1-555): 2.86e-105: 336: 100.00		PP1B_DROME (1-302): 0: 530: 85.48
+	Ce
		953872 P90902_CAEEL (115-523): 1.95e-102: 321: 38.61		GLC7A_CAEEL (5-302): 0: 536: 87.25
+	Ce
		1099876 Q95ZS1_CAEEL (115-523): 2.51e-101: 318: 38.25		GLC7A_CAEEL (5-302): 0: 536: 87.25
+	Dm
		1249016 Q8SY34_DROME (1-555): 2.86e-105: 336: 100.00		Q8T0U6_DROME (17-302): 0: 516: 87.06
+	Hs
		225129 MYPT2_HUMAN (40-518): 3.14e-88: 297: 27.54		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		225132 MYPT2_HUMAN (40-518): 3.14e-88: 297: 27.54		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Hs
		225133 MYPT2_HUMAN (40-518): 3.14e-88: 297: 27.54		PP1B_HUMAN (1-302): 0: 538: 87.79
+	Mm
		906366 MYPT1_MOUSE (110-601): 1.31e-82: 282: 27.35		PP1A_MOUSE (2-301): 0: 550: 92.33
+	Mm
		926555 MYPT1_MOUSE (110-601): 1.31e-82: 282: 27.35		PP1G_MOUSE (3-301): 0: 549: 93.31
+	Mm
		906293 MYPT2_MOUSE (108-518): 8.3e-82: 279: 28.26		PP1A_MOUSE (2-301): 0: 550: 92.33
+	Dm
		819272 Q86R99_DROME (42-458): 5.19e-90: 297: 30.95		PP1B_DROME (1-302): 0: 530: 85.48
+	Hs
		737978 PP16A_HUMAN (23-539): 4.21e-81: 267: 38.43		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		906079 PP16A_HUMAN (23-539): 4.21e-81: 267: 38.43		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Hs
		906561 PP16A_HUMAN (23-539): 4.21e-81: 267: 38.43		PP1B_HUMAN (1-302): 0: 538: 87.79
+	Dm
		1249926 Q9VUX6_DROME (42-534): 2.47e-81: 275: 28.89		Q8T0U6_DROME (17-302): 0: 516: 87.06
+	Hs
		905838 ANK2_HUMAN (2-268): 2.34e-51: 194: 18.86		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Hs
		737999 PP16B_HUMAN (19-211): 1.1e-22: 104: 12.50		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		906099 PP16B_HUMAN (19-211): 1.1e-22: 104: 12.50		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Hs
		906572 PP16B_HUMAN (19-211): 1.1e-22: 104: 12.50		PP1B_HUMAN (1-302): 0: 538: 87.79