Interactor 1: ZNT6 (Q6NXT4)
Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6)
Gene: SLC30A6

Interactor 2: ZNT5 (Q8TAD4)
Proton-coupled zinc antiporter SLC30A5 (Solute carrier family 30 member 5) (Zinc transporter 5) (ZnT-5) (ZnT-like transporter 1) (hZTL1)
Gene: SLC30A5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.913

The method score is based on:

Property Details
Experiments 21402707, 35271311, 19759014, 15994300, 25657003
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_efflux~Cation_efflux
Common GO terms GO:0005385 - zinc ion transmembrane transporter activity
GO:0005794 - Golgi apparatus
GO:0006829 - zinc ion transport
GO:0015297 - antiporter activity
GO:0032588 - trans-Golgi network membrane
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 461
Hs

1 765
+ Hs
+ Mm
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+ Mm
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+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024