HitPredict

Interactor 1: SPSB3 (Q6PJ21)
SPRY domain-containing SOCS box protein 3 (SSB-3)
Gene: SPSB3

Interactor 2: DOCK5 (Q9H7D0)
Dedicator of cytokinesis protein 5
Gene: DOCK5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1870
+	Hs
		1283458 SPSB4_HUMAN (84-312): 3.68e-72: 227: 23.05		DOCK5_HUMAN (1-1870): 0: 1989: 100.00
+	Hs
		1305208 SPSB2_HUMAN (74-312): 2.79e-65: 209: 19.69		DOCK5_HUMAN (1-1870): 0: 1989: 100.00
+	Hs
		1140768 RN123_HUMAN (55-299): 5.18e-49: 178: 13.31		DOCK5_HUMAN (1-1870): 0: 1989: 100.00
+	Hs
		1171734 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		DOCK5_HUMAN (1-1870): 0: 1989: 100.00
+	Hs
		1050486 SPSB4_HUMAN (84-312): 3.68e-72: 227: 23.05		DOCK1_HUMAN (1-1714): 0: 1913: 67.23
+	Hs
		1050479 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		DOCK1_HUMAN (1-1714): 0: 1913: 67.23
+	Hs
		1170781 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		DOCK4_HUMAN (4-1867): 0: 1688: 34.61
+	Hs
		1171581 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		DOCK9_HUMAN (945-1640): 0: 706: 16.39
+	Hs
		1127518 RN123_HUMAN (55-299): 5.18e-49: 178: 13.31		DOC11_HUMAN (945-1650): 0: 657: 15.01
+	Hs
		1171152 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		DOC10_HUMAN (968-1676): 0: 642: 15.58
+	Hs
		1171237 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		DOCK6_HUMAN (945-1651): 3.45e-175: 586: 14.76
+	Hs
		1171295 TRI67_HUMAN (105-276): 3.31e-40: 152: 21.47		DOCK7_HUMAN (59-927): 2.15e-156: 533: 14.05
+	Hs
		1140884 RN123_HUMAN (55-299): 5.18e-49: 178: 13.31		PCLO_HUMAN (1535-1852): 4.59e-09: 64.1: 8.76