HitPredict

Interactor 1: H7BYY1 (H7BYY1)
Tropomyosin 1
Gene: TPM1

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0015629 - actin cytoskeleton
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 457
+	Hs
		482968 TPM1_HUMAN (6-248): 1.35e-49: 165: 70.78		PDLI7_HUMAN (1-457): 1.42e-106: 325: 100.00
+	Hs
		995486 TPM4_HUMAN (1-248): 5.57e-49: 163: 77.82		PDLI7_HUMAN (1-457): 1.42e-106: 325: 100.00
+	Hs
		447867 TPM3_HUMAN (6-248): 5.42e-48: 161: 65.43		PDLI7_HUMAN (1-457): 1.42e-106: 325: 100.00
+	Hs
		464217 TPM2_HUMAN (5-248): 6.69e-43: 148: 63.53		PDLI7_HUMAN (1-457): 1.42e-106: 325: 100.00
+	Mm
		946698 TPM1_MOUSE (6-248): 1.22e-49: 165: 70.37		PDLI5_MOUSE (1-269): 6.13e-22: 100: 24.82
+	Hs
		464199 TPM2_HUMAN (5-248): 6.69e-43: 148: 63.53		PDLI5_HUMAN (1-269): 1.13e-22: 102: 24.82
+	Mm
		946708 TPM2_MOUSE (5-248): 4.9e-43: 148: 63.53		PDLI5_MOUSE (1-269): 6.13e-22: 100: 24.82
+	Hs
		995423 TPM4_HUMAN (1-248): 5.57e-49: 163: 77.82		TRIP6_HUMAN (335-456): 5.98e-17: 84.7: 30.40
+	Hs
		447765 TPM3_HUMAN (6-248): 5.42e-48: 161: 65.43		TRIP6_HUMAN (335-456): 5.98e-17: 84.7: 30.40
+	Hs
		1151533 Q5VU62_HUMAN (91-248): 4.08e-44: 147: 67.09		TRIP6_HUMAN (335-456): 5.98e-17: 84.7: 30.40
+	Dm
		56338 TPM2_DROME (5-246): 1.31e-39: 140: 41.32		ZASP_DROME (338-391): 8.43e-09: 60.1: 31.48