Protein: TPM1
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)

Gene: TPM1
Organism: Mus musculus
Interactions: 30
UniProt ID: P58771

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0003065 - positive regulation of heart rate by epinephrine
GO:0005200 - structural constituent of cytoskeleton
GO:0005737 - cytoplasm
GO:0005862 - muscle thin filament tropomyosin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

877761

TNNI3
Troponin I, cardiac muscle

1

6

High-throughput

0.618

High

898046

TNNT2
Troponin T, cardiac muscle

1

4

High-throughput

0.618

High

946684

TPM1
Tropomyosin alpha-1 chain

1

17

High-throughput

0.618

High

946685

ACTA
Actin, aortic smooth muscle

1

15

High-throughput

0.618

High

946693

TPM4
Tropomyosin alpha-4 chain

1

17

High-throughput

0.618

High

946697

TRI32
E3 ubiquitin-protein ligase TRIM32

1

7

Small-scale

0.536

High

108554

G3X9H5
Huntingtin

2

1

High-throughput

0.533

High

59592

A2AM57
Inversin

1

2

High-throughput

0.489

High

205005

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

1

High-throughput

0.479

High

483497

MYL3
Myosin light chain 3

1

1

High-throughput

0.479

High

946686

RGS14
Regulator of G-protein signaling 14

1

2

High-throughput

0.479

High

946689

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

3

High-throughput

0.479

High

59799

ANR16
Ankyrin repeat domain-containing protein 16

1

5

Small-scale

0.445

High

591026

KPCE
Protein kinase C epsilon type

1

5

Small-scale

0.445

High

946690

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

Small-scale

0.445

High

97575

E9PV60
WD repeat and FYVE domain containing 4

1

2

High-throughput

0.437

High

946694

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

6

High-throughput

0.437

High

946696

MT21E
Protein-lysine methyltransferase METTL21E

1

4

High-throughput

0.437

High

946698

PDLI5
PDZ and LIM domain protein 5

1

11

Small-scale

0.437

High

946699

EED
Polycomb protein EED

1

9

High-throughput

0.437

High

946701

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

1

High-throughput

0.437

High

432073

JUN
Transcription factor Jun

1

11

Small-scale

0.417

High

946695

ABI1
Abl interactor 1

1

2

High-throughput

0.417

High

946687

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.407

High

946688

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

3

High-throughput

0.407

High

946691

DJC11
DnaJ homolog subfamily C member 11

1

2

Small-scale

0.407

High

946692

SOAT1
Sterol O-acyltransferase 1

1

2

High-throughput

0.407

High

946700

FBX32
F-box only protein 32

1

0

High-throughput

0.249

Low

915500

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025