Interactor 1: UNC51 (Q23023)
Serine/threonine-protein kinase unc-51 (EC 2.7.11.1) (Uncoordinated protein 51)
Gene: unc-51

Interactor 2: UNC51 (Q23023)
Serine/threonine-protein kinase unc-51 (EC 2.7.11.1) (Uncoordinated protein 51)
Gene: unc-51

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 9242488, 15539493
Identification Methods two hybrid, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ATG1-like_MIT1~ATG1-like_MIT1, ATG1-like_MIT1~ATG1-like_MIT2, Pkinase~Pkinase
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 30 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 856
Ce

1 856
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Sc
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 11Aug2025