HitPredict

Interactor 1: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Interactor 2: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 23524951, 19225151, 20562859
Identification Methods enzymatic study, affinity chromatography technology, in-gel kinase assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG1-like_MIT1~ATG1-like_MIT1, ATG1-like_MIT1~ATG1-like_MIT2, Pkinase~Pkinase
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000421 - autophagosome membrane
GO:0000423 - mitophagy
GO:0004674 - protein serine/threonine kinase activity
and 38 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 1050
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025