HitPredict

Interactor 1: SLY1 (Q24179)
Protein sly1 homolog
Gene: Slh

Interactor 2: Q7K0X9 (Q7K0X9)
LD23667p (Syntaxin 7, isoform A) (Syntaxin 7, isoform B)
Gene: Syx7

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Sec1
Common GO terms	GO:0000149 - SNARE binding GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Dm			1 282
+	Dm
		1172792 SLY1_DROME (1-639): 0: 616: 100.00		STX1A_DROME (2-280): 1.42e-53: 177: 19.05
+	Dm
		1172811 SLY1_DROME (1-639): 0: 616: 100.00		Q9VU45_DROME (10-282): 8.47e-42: 146: 23.55
+	Dm
		1172808 SLY1_DROME (1-639): 0: 616: 100.00		Q9VR90_DROME (18-270): 5.14e-37: 136: 21.79
+	Hs
		189741 SCFD1_HUMAN (3-631): 0: 561: 56.90		STX7_HUMAN (22-276): 6.13e-48: 162: 38.46
+	Hs
		1087219 SCFD1_HUMAN (3-631): 0: 561: 56.90		STX4_HUMAN (10-280): 9.48e-43: 149: 17.67
+	Hs
		160907 SCFD1_HUMAN (3-631): 0: 561: 56.90		STX16_HUMAN (10-257): 3.31e-42: 149: 21.12
+	Hs
		1100700 SCFD1_HUMAN (3-631): 0: 561: 56.90		STX3_HUMAN (21-257): 4.18e-42: 147: 18.95
+	Mm
		204928 STXB2_MOUSE (13-634): 1.53e-171: 503: 17.52		STX1A_MOUSE (21-280): 8.42e-55: 180: 18.32
+	Rn
		746113 STXB2_RAT (10-633): 2.16e-168: 495: 17.54		STX1A_RAT (21-280): 1.25e-54: 180: 18.68
+	Hs
		746199 STXB2_HUMAN (13-633): 1.09e-167: 493: 17.86		STX2_HUMAN (15-280): 1.24e-54: 180: 17.92
+	Rn
		894401 STXB2_RAT (10-633): 2.16e-168: 495: 17.54		STX2_RAT (4-259): 3.65e-50: 168: 17.10
+	Mm
		1000451 STXB2_MOUSE (13-634): 1.53e-171: 503: 17.52		STX4_MOUSE (10-280): 1.52e-42: 149: 18.73
+	At
		1421788 KEULE_ARATH (7-631): 6.55e-163: 483: 18.91		SY121_ARATH (4-259): 4.36e-49: 167: 14.60
+	Dm
		1059140 ROP_DROME (24-631): 3.32e-157: 466: 18.20		STX1A_DROME (2-280): 1.42e-53: 177: 19.05
+	Hs
		125717 STXB3_HUMAN (27-630): 2.07e-155: 461: 16.88		STX2_HUMAN (15-280): 1.24e-54: 180: 17.92
+	Hs
		1100666 STXB2_HUMAN (13-633): 1.09e-167: 493: 17.86		STX3_HUMAN (21-257): 4.18e-42: 147: 18.95
+	At
		1192491 KEULE_ARATH (7-631): 6.55e-163: 483: 18.91		SY111_ARATH (4-259): 9.78e-43: 150: 11.20
+	Rn
		1065050 STXB2_RAT (10-633): 2.16e-168: 495: 17.54		STX3_RAT (21-257): 6.5e-36: 131: 18.55
+	Mm
		1000450 STXB3_MOUSE (28-631): 6.74e-156: 463: 17.01		STX4_MOUSE (10-280): 1.52e-42: 149: 18.73
+	Mm
		1225641 STXB2_MOUSE (13-634): 1.53e-171: 503: 17.52		STX3_MOUSE (22-257): 3.92e-18: 84: 18.62