HitPredict

Interactor 1: VP13C (Q709C8)
Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C)
Gene: VPS13C

Interactor 2: RAB2B (Q8WUD1)
Ras-related protein Rab-2B (EC 3.6.5.2)
Gene: RAB2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 3753 Hs			1 216
+	Hs
		895141 VP13C_HUMAN (1-3753): 0: 4013: 100.00		RAB2A_HUMAN (1-216): 2.31e-86: 256: 82.87
+	Hs
		918895 VP13C_HUMAN (1-3753): 0: 4013: 100.00		RAB1A_HUMAN (3-216): 9.52e-84: 249: 43.93
+	Hs
		1173713 VP13C_HUMAN (1-3753): 0: 4013: 100.00		RAB1B_HUMAN (3-216): 1.37e-82: 245: 42.52
+	Hs
		896642 VP13C_HUMAN (1-3753): 0: 4013: 100.00		RAB14_HUMAN (3-215): 4.02e-82: 245: 55.87
+	Hs
		914157 VP13C_HUMAN (1-3753): 0: 4013: 100.00		RB11A_HUMAN (3-216): 1.65e-81: 243: 46.26
+	Hs
		591900 VP13C_HUMAN (1-3753): 0: 4013: 100.00		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29
+	Hs
		895235 VP13A_HUMAN (1-1615): 0: 1188: 38.34		RAB2A_HUMAN (1-216): 2.31e-86: 256: 82.87
+	Hs
		914296 VP13A_HUMAN (1-1615): 0: 1188: 38.34		RB11A_HUMAN (3-216): 1.65e-81: 243: 46.26
+	Hs
		591985 VP13A_HUMAN (1-1615): 0: 1188: 38.34		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29
+	Hs
		47676 A0AUL9_HUMAN (4-362): 8.15e-56: 206: 14.71		RAB1A_HUMAN (3-216): 9.52e-84: 249: 43.93
+	Hs
		591971 ATG2B_HUMAN (4-362): 1.94e-59: 231: 16.75		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29
+	Hs
		591865 ATG2A_HUMAN (4-362): 4.38e-52: 206: 14.71		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29
+	Hs
		591879 VP13D_HUMAN (1041-2048): 1.94e-43: 179: 14.23		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29
+	Hs
		914175 VP13B_HUMAN (2-275): 5.08e-38: 160: 21.22		RB11A_HUMAN (3-216): 1.65e-81: 243: 46.26
+	Dm
		185550 Q9VAD3_DROME (3-346): 6.09e-32: 140: 15.81		RAB2_DROME (1-216): 7.46e-88: 259: 83.33
+	Hs
		591908 VP13B_HUMAN (2-275): 5.08e-38: 160: 21.22		RAB4A_HUMAN (2-188): 8.55e-74: 224: 58.29