Protein: PLXA2
Plexin-A2 (Semaphorin receptor OCT)

Gene: PLXA2, PLXNA2
Organism: Homo sapiens
Interactions: 85
UniProt ID: O75051

Gene Ontology (top 5):
GO:0001756 - somitogenesis
GO:0002116 - semaphorin receptor complex
GO:0005886 - plasma membrane
GO:0007416 - synapse assembly
GO:0017154 - semaphorin receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

269657

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

3

High-throughput

0.811

High

269643

SG1D1
Secretoglobin family 1D member 1

2

6

High-throughput

0.726

High

269717

ST14
Suppressor of tumorigenicity 14 protein

1

15

High-throughput

0.691

High

269646

TNFA
Tumor necrosis factor

3

1

High-throughput

0.667

High

269668

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

16

High-throughput

0.667

High

269652

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

2

9

High-throughput

0.628

High

269675

CC50B
Cell cycle control protein 50B

2

3

High-throughput

0.628

High

269690

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

4

High-throughput

0.628

High

269712

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

2

4

High-throughput

0.628

High

269682

BTNL3
Butyrophilin-like protein 3

1

9

High-throughput

0.618

High

164195

NRP1
Neuropilin-1

1

20

Small-scale

0.618

High

269644

RASH
GTPase HRas

1

15

High-throughput

0.618

High

269645

RASK
GTPase KRas

1

19

High-throughput

0.618

High

269669

TAZ
Tafazzin

3

3

High-throughput

0.609

High

269677

SUSD4
Sushi domain-containing protein 4

3

2

High-throughput

0.609

High

269647

IGHD
Immunoglobulin heavy constant delta

1

6

High-throughput

0.575

High

142191

CCL22
C-C motif chemokine 22

2

2

High-throughput

0.574

High

269661

DEF1
Neutrophil defensin 1

2

5

High-throughput

0.574

High

269663

DEF5
Defensin alpha 5

2

5

High-throughput

0.574

High

269665

OS9
Protein OS-9

2

2

High-throughput

0.574

High

269676

MPPE1
Metallophosphoesterase 1

2

1

High-throughput

0.574

High

269695

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

5

High-throughput

0.574

High

269696

TECT2
Tectonic-2

2

1

High-throughput

0.574

High

269698

TAFA4
Chemokine-like protein TAFA-4

2

2

High-throughput

0.574

High

269648

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

19

High-throughput

0.536

High

269651

LEG1
Galectin-1

1

7

High-throughput

0.536

High

269654

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

18

High-throughput

0.536

High

269656

RYK
Tyrosine-protein kinase RYK

1

20

High-throughput

0.536

High

269658

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.536

High

269664

SLAF1
Signaling lymphocytic activation molecule

1

8

High-throughput

0.536

High

269671

HFE
Hereditary hemochromatosis protein

1

8

High-throughput

0.536

High

269681

LYPD2
Ly6/PLAUR domain-containing protein 2

1

6

High-throughput

0.536

High

269684

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

3

High-throughput

0.536

High

269706

CRLF2
Cytokine receptor-like factor 2

1

9

High-throughput

0.536

High

269711

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

4

High-throughput

0.536

High

269713

CLC4A
C-type lectin domain family 4 member A

1

13

High-throughput

0.536

High

269715

PCDB1
Protocadherin beta-1

1

6

High-throughput

0.536

High

269642

LYZL6
Lysozyme-like protein 6

1

4

High-throughput

0.489

High

269649

C1QA
Complement C1q subcomponent subunit A

1

5

High-throughput

0.489

High

269650

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

269653

CAH6
Carbonic anhydrase 6

1

3

High-throughput

0.489

High

269659

MFAP4
Microfibril-associated glycoprotein 4

1

3

High-throughput

0.489

High

269660

EP3B
Epididymal secretory protein E3-beta

1

4

High-throughput

0.489

High

269667

EP3A
Epididymal secretory protein E3-alpha

1

4

High-throughput

0.489

High

269670

CL12B
C-type lectin domain family 12 member B

1

17

High-throughput

0.489

High

269673

DB135
Beta-defensin 135

1

3

High-throughput

0.489

High

269679

BRID5
BRICHOS domain-containing protein 5

1

6

High-throughput

0.489

High

269683

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

3

High-throughput

0.489

High

269688

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

3

High-throughput

0.489

High

269693

CA054
Uncharacterized protein C1orf54

1

8

High-throughput

0.489

High

269694

PATE1
Prostate and testis expressed protein 1

1

4

High-throughput

0.489

High

269697

LCFC1
Sperm-egg fusion protein LLCFC1

1

1

High-throughput

0.489

High

269705

CST9L
Cystatin-9-like

1

4

High-throughput

0.489

High

269710

FBX2
F-box only protein 2

1

15

High-throughput

0.489

High

269714

HYOU1
Hypoxia up-regulated protein 1

1

7

High-throughput

0.489

High

269691

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.486

High

188742

TMPS2
Transmembrane protease serine 2

1

15

High-throughput

0.479

High

269707

TMPS4
Transmembrane protease serine 4

1

15

High-throughput

0.479

High

269666

UBP2L
Ubiquitin-associated protein 2-like

1

3

Small-scale

0.464

High

269686

HACE1
E3 ubiquitin-protein ligase HACE1

1

1

Small-scale

0.457

High

222235

PSCA
Prostate stem cell antigen

1

2

High-throughput

0.445

High

254669

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.445

High

269702

S13A1
Solute carrier family 13 member 1

1

1

High-throughput

0.445

High

269708

IFT80
Intraflagellar transport protein 80 homolog

1

1

Small-scale

0.439

High

74409

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

8

High-throughput

0.437

High

85522

HNRC3
Heterogeneous nuclear ribonucleoprotein C-like 3

1

9

High-throughput

0.437

High

256555

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

8

High-throughput

0.437

High

269655

CALX
Calnexin

1

11

High-throughput

0.437

High

269678

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.437

High

269685

DHX37
Probable ATP-dependent RNA helicase DHX37

1

2

Small-scale

0.417

High

269692

PDC6I
Programmed cell death 6-interacting protein

1

3

Small-scale

0.417

High

269699

MF14A
Hippocampus abundant transcript 1 protein

1

1

High-throughput

0.407

High

269700

GPHA2
Glycoprotein hormone alpha-2

3

0

High-throughput

0.347

High

252212

ISK4
Serine protease inhibitor Kazal-type 4

2

0

High-throughput

0.328

High

269703

LACRT
Extracellular glycoprotein lacritin

2

0

High-throughput

0.328

High

269716

INSL5
Insulin-like peptide INSL5

2

0

High-throughput

0.328

High

269709

NUFP1
FMR1-interacting protein NUFIP1

2

0

High-throughput

0.318

High

269662

NDP
Norrin

1

0

High-throughput

0.279

Low

269672

DB136
Defensin beta 136

1

0

High-throughput

0.279

Low

269680

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

269689

WFD11
Protein WFDC11

1

0

High-throughput

0.279

Low

269701

RETNB
Resistin-like beta

1

0

High-throughput

0.279

Low

269704

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

269687

FNBP4
Formin-binding protein 4

1

0

Small-scale

0.265

Low

269674

DB109
Beta-defensin 109B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025