HitPredict

Interactor 1: MD13L (Q71F56)
Mediator of RNA polymerase II transcription subunit 13-like (Mediator complex subunit 13-like) (Thyroid hormone receptor-associated protein 2) (Thyroid hormone receptor-associated protein complex 240 kDa component-like)
Gene: MED13L

Interactor 2: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	24981860, 26186194, 28514442, 33961781, 32707033, 23602568
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2210 Hs			1 502
+	Hs
		826302 MD13L_HUMAN (1-2210): 0: 3763: 100.00		CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69
+	Hs
		73031 MD13L_HUMAN (1-2210): 0: 3763: 100.00		B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00
+	Mm
		1131974 MED13_MOUSE (4-2210): 0: 3229: 51.97		CDK8_MOUSE (1-502): 7.79e-153: 445: 76.49
+	Hs
		1314888 MED13_HUMAN (4-2210): 0: 3181: 51.34		CDK19_HUMAN (1-502): 1.67e-157: 459: 100.00
+	Hs
		826370 MED13_HUMAN (4-2210): 0: 3181: 51.34		CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69
+	Hs
		73048 MED13_HUMAN (4-2210): 0: 3181: 51.34		B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00
+	Dm
		1182305 MED13_DROME (943-1152): 8.63e-10: 66.7: 23.77		CDK8_DROME (1-413): 7.19e-138: 407: 77.24