Interactor 1: CALYP (Q7K5N4)
Ubiquitin carboxyl-terminal hydrolase calypso (EC 3.4.19.12) (BRCA1-associated protein 1 homolog) (BAP1 homolog) (Polycomb group protein calypso)
Gene: caly

Interactor 2: ASX (Q9V727)
Polycomb group protein Asx (Protein additional sex combs)
Gene: ASX

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.880

The method score is based on:

Property Details
Experiments 30258054, 30639226, 20436459
Identification Methods x-ray crystallography, pull down, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ASXH~Peptidase_C12, ASXH~UCH_C
Common GO terms GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0035517 - PR-DUB complex
GO:0040029 - epigenetic regulation of gene expression
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 471
Dm

1 1669
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
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+ Hs

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Last updated: 15 Jul 2024