HitPredict

Interactor 1: SNP23 (O00161)
Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23)
Gene: SNAP23

Interactor 2: STX19 (Q8N4C7)
Syntaxin-19
Gene: STX19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex GO:0031629 - synaptic vesicle fusion to presynaptic active zone membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Hs			1 294
+	Hs
		118037 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1A_HUMAN (8-288): 8.61e-68: 214: 28.72
+	Hs
		118010 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1B_HUMAN (8-288): 3.71e-67: 212: 28.01
+	Hs
		117977 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX2_HUMAN (24-288): 5.11e-65: 207: 26.32
+	Mm
		140165 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX1A_MOUSE (8-288): 1.56e-68: 216: 28.72
+	Rn
		250768 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX1B_RAT (8-288): 3.71e-67: 212: 28.01
+	Hs
		117936 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX11_HUMAN (1-290): 1.64e-58: 190: 36.43
+	Hs
		66335 A8K287_HUMAN (1-211): 1.06e-71: 218: 100.00		STX11_HUMAN (1-290): 1.64e-58: 190: 36.43
+	Hs
		118025 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX4_HUMAN (8-289): 1.34e-56: 186: 27.47
+	Dm
		1098103 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		STX1A_DROME (28-289): 4.7e-64: 204: 25.10
+	Hs
		118028 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX3_HUMAN (1-281): 1.76e-52: 175: 29.08
+	Ce
		183449 O62414_CAEEL (4-209): 2.49e-58: 184: 46.60		STX1A_CAEEL (2-288): 4.39e-66: 209: 27.08
+	Rn
		250772 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX4_RAT (8-289): 4.76e-53: 176: 25.00
+	Rn
		250771 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX3_RAT (1-281): 1.79e-51: 172: 28.72
+	Hs
		117929 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX7_HUMAN (58-280): 9.42e-48: 162: 17.26
+	Mm
		140169 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX3_MOUSE (1-281): 3.24e-51: 171: 28.72
+	Hs
		118048 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX12_HUMAN (53-288): 5.3e-46: 157: 18.33
+	At
		1351792 SNP33_ARATH (1-210): 2.42e-60: 192: 22.54		SY121_ARATH (20-283): 1.04e-54: 182: 16.54
+	At
		1114737 SNP33_ARATH (1-210): 2.42e-60: 192: 22.54		SY111_ARATH (13-283): 6.95e-47: 161: 15.11
+	Dm
		1182812 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		STX4_DROME (34-284): 9.59e-45: 156: 15.54
+	Dm
		1366722 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q9VR90_DROME (4-287): 2.29e-44: 155: 10.94