HitPredict

Interactor 1: PP1R7 (Q3UM45)
Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)
Gene: Ppp1r7

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_4~SH3_2
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 361 Mm			1 1730
+	Mm
		1193798 LRRC7_MOUSE (1-161): 1.8e-19: 92.2: 15.85		SHAN3_MOUSE (1-1730): 0: 649: 100.00
+	Mm
		503540 LRC4B_MOUSE (253-360): 8.04e-13: 71.5: 26.79		SHAN3_MOUSE (1-1730): 0: 649: 100.00
+	Hs
		1399277 LRRC7_HUMAN (1-161): 6.05e-19: 90.7: 15.85		SHAN3_HUMAN (7-1730): 0: 615: 94.38
+	Hs
		1122375 SCRIB_HUMAN (1-250): 4.74e-33: 132: 16.13		ANR50_HUMAN (197-1139): 3.34e-53: 208: 10.76
+	Hs
		1416701 LGR4_HUMAN (1-353): 2.57e-41: 156: 18.43		KDIS_HUMAN (258-532): 5.17e-28: 126: 12.36
+	Hs
		920434 FLII_HUMAN (12-270): 1.08e-27: 116: 18.71		DAPK1_HUMAN (2-202): 2.33e-39: 163: 15.20
+	Hs
		1295477 LRC49_HUMAN (188-360): 6.19e-17: 84.2: 26.59		MIB1_HUMAN (190-655): 1.42e-49: 194: 11.02
+	Hs
		247460 PHLP1_HUMAN (55-361): 1.17e-34: 137: 17.28		KDIS_HUMAN (258-532): 5.17e-28: 126: 12.36
+	Hs
		1399285 LRRC7_HUMAN (1-161): 6.05e-19: 90.7: 15.85		SHAN1_HUMAN (327-1725): 6.72e-26: 119: 13.94