HitPredict

Interactor 1: Q3YMU0 (Q3YMU0)
Protein disulfide-isomerase (EC 5.3.4.1)
Gene: ERp60

Interactor 2: THIO2 (Q9V429)
Thioredoxin-2 (DmTrx-2)
Gene: Trx2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 489 Dm			1 106
+	Dm
		1191679 Q3YMU0_DROME (1-489): 4.25e-152: 444: 100.00		PDIA6_DROME (3-94): 5.93e-27: 104: 18.09
+	Hs
		452382 PDIA1_HUMAN (15-469): 1.44e-126: 379: 33.05		THIOM_HUMAN (5-106): 3.58e-34: 117: 37.86
+	Hs
		566571 PDIA3_HUMAN (2-474): 1.66e-132: 394: 46.42		PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02
+	Hs
		717371 PDIA3_HUMAN (2-474): 1.66e-132: 394: 46.42		PDIA3_HUMAN (3-104): 3.22e-26: 102: 24.30
+	Hs
		452145 PDIA1_HUMAN (15-469): 1.44e-126: 379: 33.05		PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02
+	Dm
		929527 PDI_DROME (5-489): 1.94e-114: 348: 32.66		THIO2_DROME (1-106): 1.89e-38: 126: 100.00
+	At
		1318507 PDI11_ARATH (3-473): 7.59e-109: 334: 32.44		TRXY2_ARATH (6-106): 2.94e-35: 119: 35.29
+	Dm
		929528 PDI_DROME (5-489): 1.94e-114: 348: 32.66		PDIA6_DROME (3-94): 5.93e-27: 104: 18.09
+	Nc
		1274127 Q7S399_NEUCR (22-486): 2.29e-110: 337: 34.40		ERP38_NEUCR (3-105): 4.95e-28: 105: 26.61
+	Ce
		1165053 PDI1_CAEEL (6-487): 2.38e-107: 329: 28.60		PDI2_CAEEL (3-103): 3.39e-25: 99.4: 23.81
+	At
		1192558 PDI11_ARATH (3-473): 7.59e-109: 334: 32.44		TRXH3_ARATH (19-93): 5.03e-17: 72: 48.00
+	Hs
		566671 PDIA5_HUMAN (122-487): 3.77e-36: 142: 14.36		PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02
+	Hs
		566761 TXND5_HUMAN (12-133): 1.16e-30: 125: 33.61		PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02
+	Mm
		1021743 ERP44_MOUSE (359-488): 2.66e-25: 109: 22.06		THIOM_MOUSE (5-106): 1.29e-33: 115: 38.84
+	Mm
		1362256 ERP44_MOUSE (359-488): 2.66e-25: 109: 22.06		TXND5_MOUSE (24-106): 1.13e-27: 105: 26.14
+	Hs
		566819 ERP44_HUMAN (357-488): 4.89e-25: 108: 20.29		PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02
+	Mm
		697731 ERP44_MOUSE (359-488): 2.66e-25: 109: 22.06		PDIA3_MOUSE (3-104): 1.92e-25: 100: 23.36
+	Rn
		801669 PDIA4_RAT (364-488): 7.97e-25: 109: 32.81		PDIA4_RAT (3-105): 5.81e-24: 96.4: 23.85