Interactor 1: PEN2 (Q86BE9)
Gamma-secretase subunit pen-2 (Presenilin enhancer protein 2)
Gene: pen-2

Interactor 2: APH1 (Q9VQG2)
Gamma-secretase subunit Aph-1 (Presenilin-stabilization factor)
Gene: aph-1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 20421416, 15644323
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005770 - late endosome
GO:0006509 - membrane protein ectodomain proteolysis
GO:0007219 - Notch signaling pathway
GO:0007220 - Notch receptor processing
GO:0016485 - protein processing
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 101
Dm

1 238
+ Hs
+ Hs
+ Ce

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Last updated: 15 Jul 2024