Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15371411
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0006909 - phagocytosis
GO:0006955 - immune response
GO:0032729 - positive regulation of type II interferon production
GO:0032735 - positive regulation of interleukin-12 production
and 4 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 839
Hs

1 426
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Last updated: 15 Jul 2024