HitPredict

Interactor 1: TAXB1 (Q86VP1)
Tax1-binding protein 1 (TRAF6-binding protein)
Gene: TAX1BP1

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	26451915, 29940186, 26971995, 31371777, 17635994
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology, two hybrid
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 789 Hs			1 1294
+	Hs
		1025598 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		149417 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1051512 DCTN1_HUMAN (173-498): 9.09e-17: 87.3: 18.71		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1025566 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		528370 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYH6_HUMAN (760-1113): 5.54e-10: 66.2: 18.89
+	Hs
		724805 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		725151 CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00		MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54
+	Hs
		1343920 MYO5A_HUMAN (269-660): 1.32e-13: 77.3: 14.15		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		1268099 MY18A_HUMAN (251-658): 5.76e-13: 75: 11.46		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Mm
		1303337 MYO5A_MOUSE (269-660): 6.97e-14: 78: 14.63		MYO5A_MOUSE (710-1184): 1.64e-18: 94.2: 8.65
+	Hs
		148460 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		148461 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54
+	Hs
		148466 CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44		MYH11_HUMAN (844-1177): 1.17e-09: 65.5: 18.55
+	Hs
		725097 MYH11_HUMAN (315-745): 1.27e-16: 87: 10.96		MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54
+	Hs
		724687 MYH10_HUMAN (290-756): 5.81e-16: 84.7: 10.02		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		725095 MYH10_HUMAN (290-756): 5.81e-16: 84.7: 10.02		MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54
+	Hs
		725086 MYO5A_HUMAN (269-660): 1.32e-13: 77.3: 14.15		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		502901 MYH3_HUMAN (72-511): 3.76e-13: 75.8: 10.39		MYH6_HUMAN (760-1113): 5.54e-10: 66.2: 18.89
+	Hs
		724943 MY18A_HUMAN (251-658): 5.76e-13: 75: 11.46		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70