HitPredict

Interactor 1: CDKL4 (Q5MAI5)
Cyclin-dependent kinase-like 4 (EC 2.7.11.22)
Gene: CDKL4

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 379 Hs			1 2054
+	Hs
		667955 CDK2_HUMAN (1-292): 1.42e-139: 400: 37.76		MY18A_HUMAN (1-2054): 0: 1274: 100.00
+	Hs
		1025301 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH13_HUMAN (962-1986): 7.75e-55: 214: 14.89
+	Hs
		667590 CDK2_HUMAN (1-292): 1.42e-139: 400: 37.76		MYH9_HUMAN (1257-2002): 1.21e-52: 207: 16.52
+	Hs
		556914 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH7_HUMAN (958-1715): 1.02e-37: 158: 11.34
+	Hs
		556845 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH1_HUMAN (947-1741): 5.2e-35: 149: 12.82
+	Hs
		563005 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH6_HUMAN (980-1726): 5.73e-35: 149: 11.55
+	Hs
		1025300 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH2_HUMAN (970-1815): 9.43e-35: 148: 13.07
+	Hs
		563043 CDK2_HUMAN (1-292): 1.42e-139: 400: 37.76		MYH8_HUMAN (1635-2054): 1.33e-27: 125: 16.67
+	Hs
		535930 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH3_HUMAN (1587-2054): 2.81e-28: 127: 15.29
+	Hs
		563048 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH8_HUMAN (1635-2054): 1.33e-27: 125: 16.67
+	Hs
		1097173 MK07_HUMAN (2-365): 4.05e-130: 394: 24.80		MYO5B_HUMAN (1490-2053): 1.93e-21: 104: 12.21
+	Hs
		667591 CDK2_HUMAN (1-292): 1.42e-139: 400: 37.76		MYH10_HUMAN (1178-1641): 2.61e-18: 94.4: 14.56
+	Hs
		668087 CDK2_HUMAN (1-292): 1.42e-139: 400: 37.76		MYO5A_HUMAN (1723-2054): 7.65e-15: 83.3: 12.94
+	Hs
		1097179 MK07_HUMAN (2-365): 4.05e-130: 394: 24.80		MYO5A_HUMAN (1723-2054): 7.65e-15: 83.3: 12.94
+	Hs
		1025302 CDK3_HUMAN (1-304): 1.69e-137: 395: 38.56		MYH15_HUMAN (1248-1834): 8.83e-09: 63.2: 18.86
+	Hs
		772679 CDK7_HUMAN (2-288): 1.64e-62: 205: 38.87		MYH9_HUMAN (1257-2002): 1.21e-52: 207: 16.52
+	Hs
		773129 CDK7_HUMAN (2-288): 1.64e-62: 205: 38.87		MYH10_HUMAN (1178-1641): 2.61e-18: 94.4: 14.56