HitPredict

Interactor 1: Q5T8C6 (Q5T8C6)
Cell division cycle 16
Gene: CDC16

Interactor 2: ANC2 (Q9UJX6)
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)
Gene: ANAPC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Cullin~TPR_12
Common GO terms	GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Hs			1 822
+	Hs
		1093082 CDC16_HUMAN (1-475): 2.47e-91: 291: 84.79		ANC2_HUMAN (1-822): 0: 884: 100.00
+	Hs
		718655 CDC27_HUMAN (13-392): 4.14e-35: 141: 11.02		ANC2_HUMAN (1-822): 0: 884: 100.00
+	Hs
		1460747 APC7_HUMAN (28-458): 6.25e-16: 82.3: 12.90		ANC2_HUMAN (1-822): 0: 884: 100.00
+	Hs
		1460723 CDC23_HUMAN (3-289): 7.31e-14: 75.7: 9.49		ANC2_HUMAN (1-822): 0: 884: 100.00
+	Dm
		1440434 Q9I7L8_DROME (1-461): 1.31e-54: 195: 18.53		Q9W1E5_DROME (73-819): 0: 634: 37.15
+	At
		75109 CDC16_ARATH (13-402): 2.64e-48: 175: 32.45		APC2_ARATH (46-819): 0: 632: 29.28
+	At
		1057509 CD27A_ARATH (114-387): 1e-45: 171: 16.00		APC2_ARATH (46-819): 0: 632: 29.28
+	At
		1300972 CD27B_ARATH (118-400): 4.59e-43: 164: 16.20		APC2_ARATH (46-819): 0: 632: 29.28
+	Hs
		1092959 CDC16_HUMAN (1-475): 2.47e-91: 291: 84.79		CUL3_HUMAN (243-808): 3.87e-134: 419: 14.93
+	At
		1300980 CDC23_ARATH (10-199): 8.8e-13: 72.2: 11.50		APC2_ARATH (46-819): 0: 632: 29.28
+	Hs
		185679 OGT1_HUMAN (13-200): 1.27e-19: 94.2: 10.94		CUL4B_HUMAN (244-812): 1.54e-143: 448: 16.06
+	Hs
		1115126 CDC23_HUMAN (3-289): 7.31e-14: 75.7: 9.49		CUL4A_HUMAN (244-806): 2.51e-150: 460: 16.42
+	Sc
		792497 CDC27_YEAST (205-401): 4.84e-19: 92.2: 13.46		APC2_YEAST (257-820): 2.35e-136: 427: 22.12
+	Hs
		185678 OGT1_HUMAN (13-200): 1.27e-19: 94.2: 10.94		CUL3_HUMAN (243-808): 3.87e-134: 419: 14.93
+	Sc
		486799 CDC16_YEAST (19-432): 2.53e-15: 80.7: 11.09		APC2_YEAST (257-820): 2.35e-136: 427: 22.12
+	Sc
		597626 CDC23_YEAST (39-402): 3.44e-15: 79.9: 10.07		APC2_YEAST (257-820): 2.35e-136: 427: 22.12
+	Hs
		1114607 APC7_HUMAN (28-458): 6.25e-16: 82.3: 12.90		CUL3_HUMAN (243-808): 3.87e-134: 419: 14.93
+	Sp
		836488 CUT9_SCHPO (16-285): 7.81e-14: 75.7: 9.39		APC2_SCHPO (237-818): 2.76e-125: 393: 29.67
+	Sp
		522329 APC3_SCHPO (7-236): 1.62e-12: 71.8: 12.17		APC2_SCHPO (237-818): 2.76e-125: 393: 29.67
+	Xl
		91446 Q6GQ04_XENLA (14-304): 2.05e-28: 121: 12.72		C6ZIW0_XENLA (39-359): 1.91e-105: 329: 54.21