HitPredict

Interactor 1: NUDC3 (Q8IVD9)
NudC domain-containing protein 3
Gene: NUDCD3

Interactor 2: HCFC2 (Q9Y5Z7)
Host cell factor 2 (HCF-2) (C2 factor)
Gene: HCFC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 792
+	Hs
		1377063 NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38		HCFC2_HUMAN (1-792): 0: 767: 100.00
+	Hs
		985637 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		Q05C05_HUMAN (8-538): 1.76e-122: 380: 51.69
+	Hs
		848248 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		HCFC1_HUMAN (513-789): 6.49e-98: 336: 42.81
+	Hs
		1217428 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLDC3_HUMAN (58-426): 1.21e-60: 211: 19.95
+	Hs
		1217438 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL1_HUMAN (2-253): 5.7e-51: 192: 13.78
+	Hs
		1049257 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KEAP1_HUMAN (135-472): 1.42e-49: 186: 10.79
+	Hs
		299523 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH18_HUMAN (179-506): 3.99e-41: 161: 10.91
+	Hs
		1217465 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLDC2_HUMAN (5-308): 2.57e-40: 155: 18.79
+	Hs
		1217431 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL4_HUMAN (2-136): 1.39e-24: 111: 16.20
+	Hs
		1217405 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLDC1_HUMAN (1-166): 5.87e-23: 104: 20.00
+	Hs
		1161736 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLD10_HUMAN (186-356): 7.78e-17: 85.8: 19.57
+	Hs
		1217464 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH20_HUMAN (353-486): 7.9e-11: 67.6: 5.97
+	Hs
		1159387 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		FBX42_HUMAN (184-356): 8.06e-10: 64.3: 29.05
+	Hs
		1237058 NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38		KLDC1_HUMAN (1-166): 5.87e-23: 104: 20.00
+	Hs
		1261421 NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11		KLHL1_HUMAN (2-253): 5.7e-51: 192: 13.78
+	Hs
		1261414 NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11		KLHL4_HUMAN (2-136): 1.39e-24: 111: 16.20
+	Hs
		1159402 NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11		FBX42_HUMAN (184-356): 8.06e-10: 64.3: 29.05