Protein: SAS6
Spindle assembly abnormal protein 6 homolog (HsSAS-6) (Spindle assembly defective protein 6)

Gene: SAS6, SASS6
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q6UVJ0

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005814 - centriole
GO:0007099 - centriole replication
GO:0007283 - spermatogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1149308

STIL
SCL-interrupting locus protein

4

1

Small-scale

0.686

High

1248201

CPAP
Centrosomal P4.1-associated protein

4

18

Small-scale

0.673

High

1226141

CP135
Centrosomal protein of 135 kDa

2

16

Small-scale

0.644

High

1107843

SQSTM
Sequestosome-1

3

5

High-throughput

0.640

High

1248190

AASD1
Alanyl-tRNA editing protein Aarsd1

2

1

High-throughput

0.628

High

1248206

ABI2
Abl interactor 2

2

11

High-throughput

0.628

High

1248171

ENTR1
Endosome-associated-trafficking regulator 1

3

0

High-throughput

0.613

High

1248183

FYCO1
FYVE and coiled-coil domain-containing protein 1

3

18

High-throughput

0.609

High

50909

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.602

High

136101

PLK4
Serine/threonine-protein kinase PLK4

2

14

Small-scale

0.584

High

213175

CP110
Centriolar coiled-coil protein of 110 kDa

2

1

High-throughput

0.584

High

324160

CE152
Centrosomal protein of 152 kDa

2

16

High-throughput

0.584

High

341968

CEP43
Centrosomal protein 43

2

1

High-throughput

0.584

High

668635

APC
Adenomatous polyposis coli protein

2

10

High-throughput

0.584

High

1143370

PCM1
Pericentriolar material 1 protein

2

1

High-throughput

0.584

High

1212789

UBR4
E3 ubiquitin-protein ligase UBR4

2

1

High-throughput

0.584

High

1248149

LRC49
Leucine-rich repeat-containing protein 49

2

9

High-throughput

0.584

High

1248150

CEP97
Centrosomal protein of 97 kDa

2

3

High-throughput

0.584

High

1248155

NIN
Ninein

2

19

High-throughput

0.584

High

1248158

NEDD1
Protein NEDD1

2

3

High-throughput

0.584

High

1248159

ALMS1
Centrosome-associated protein ALMS1

2

4

High-throughput

0.584

High

1248161

DLG5
Disks large homolog 5

2

7

High-throughput

0.584

High

1248185

LZTS2
Leucine zipper putative tumor suppressor 2

2

18

High-throughput

0.584

High

1248216

CP131
Centrosomal protein of 131 kDa

2

16

High-throughput

0.584

High

1248214

SCOC
Short coiled-coil protein

2

1

High-throughput

0.574

High

1248168

FBXW7
F-box/WD repeat-containing protein 7

1

8

Small-scale

0.561

High

290046

OFD1
Centriole and centriolar satellite protein OFD1

2

0

High-throughput

0.559

High

1248163

PIBF1
Progesterone-induced-blocking factor 1

2

0

High-throughput

0.559

High

1248202

Q9HCK3
KIAA1569 protein

2

0

High-throughput

0.559

High

1248220

ADIP
Afadin- and alpha-actinin-binding protein

2

0

High-throughput

0.559

High

319223

FCSD2
F-BAR and double SH3 domains protein 2

2

5

High-throughput

0.553

High

1248142

CATAC
Centrosomal AT-AC splicing factor

1

0

Small-scale

0.537

High

1248169

FBXW5
F-box/WD repeat-containing protein 5

1

0

Small-scale

0.537

High

789144

NUP62
Nuclear pore glycoprotein p62

1

3

High-throughput

0.536

High

1091015

BFSP1
Filensin

1

20

High-throughput

0.536

High

1121429

KEAP1
Kelch-like ECH-associated protein 1

1

4

High-throughput

0.536

High

1228667

C102B
Coiled-coil domain-containing protein 102B

1

17

High-throughput

0.536

High

1248193

TBD2A
TBC1 domain family member 2A

1

10

High-throughput

0.536

High

1248197

RABE2
Rab GTPase-binding effector protein 2

1

18

High-throughput

0.536

High

1225361

WAC2A
WASH complex subunit 2A

2

1

High-throughput

0.533

High

1248217

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

3

High-throughput

0.533

High

843679

HD
Huntingtin

1

4

High-throughput

0.515

High

1248167

APBB2
Amyloid beta precursor protein binding family B member 2

1

2

High-throughput

0.515

High

289358

CTAG2
Cancer/testis antigen 2

1

0

High-throughput

0.513

High

807950

SMBP2
DNA-binding protein SMUBP-2

1

0

High-throughput

0.513

High

1248136

ZN365
Protein ZNF365

1

0

High-throughput

0.513

High

1248166

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1248215

FZR1
Fizzy-related protein homolog

1

7

Small-scale

0.512

High

209288

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

7

High-throughput

0.489

High

300663

KRT37
Keratin, type I cuticular Ha7

1

20

High-throughput

0.489

High

630302

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

10

High-throughput

0.489

High

1007487

KRT83
Keratin, type II cuticular Hb3

1

19

High-throughput

0.489

High

1226908

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.489

High

1248138

EFL1
Elongation factor-like GTPase 1

1

4

High-throughput

0.489

High

1248139

K1C27
Keratin, type I cytoskeletal 27

1

20

High-throughput

0.489

High

1248144

EX3L1
Exocyst complex component 3-like protein

1

1

High-throughput

0.489

High

1248146

C2CD5
C2 domain-containing protein 5

1

2

High-throughput

0.489

High

1248153

ENTD1
ENTH domain-containing protein 1

1

4

High-throughput

0.489

High

1248162

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

1

1

High-throughput

0.489

High

1248164

S39A7
Zinc transporter SLC39A7

1

8

High-throughput

0.489

High

1248194

T126A
Transmembrane protein 126A

1

1

High-throughput

0.489

High

159708

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

10

High-throughput

0.479

High

161625

RGPD8
RANBP2-like and GRIP domain-containing protein 8

1

2

High-throughput

0.479

High

177003

CE290
Centrosomal protein of 290 kDa

1

19

High-throughput

0.479

High

186765

P73
Tumor protein p73

1

5

High-throughput

0.479

High

208687

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

5

High-throughput

0.479

High

215317

TXNL1
Thioredoxin-like protein 1

1

3

High-throughput

0.479

High

242043

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

244586

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

6

High-throughput

0.479

High

340166

PCNT
Pericentrin

1

18

High-throughput

0.479

High

515794

RGPD1
RANBP2-like and GRIP domain-containing protein 1

1

3

High-throughput

0.479

High

946423

MTPN
Myotrophin

1

7

High-throughput

0.479

High

986509

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.479

High

1007715

RAE1L
mRNA export factor RAE1

1

3

High-throughput

0.479

High

1033705

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

1058865

ZO1
Tight junction protein 1

1

4

High-throughput

0.479

High

1140449

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

1178588

KIF7
Kinesin-like protein KIF7

1

4

High-throughput

0.479

High

1210879

CE170
Centrosomal protein of 170 kDa

1

5

High-throughput

0.479

High

1214934

CCD18
Coiled-coil domain-containing protein 18

1

18

High-throughput

0.479

High

1215460

CE162
Centrosomal protein of 162 kDa

1

18

High-throughput

0.479

High

1217468

CE350
Centrosome-associated protein 350

1

19

High-throughput

0.479

High

1248147

MIB1
E3 ubiquitin-protein ligase MIB1

1

4

High-throughput

0.479

High

1248148

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

19

High-throughput

0.479

High

1248154

CNTRB
Centrobin

1

18

High-throughput

0.479

High

1248160

BICD2
Protein bicaudal D homolog 2

1

18

High-throughput

0.479

High

1248170

TTC28
Tetratricopeptide repeat protein 28

1

8

High-throughput

0.479

High

1248175

BICD1
Protein bicaudal D homolog 1

1

18

High-throughput

0.479

High

1248178

CEP63
Centrosomal protein of 63 kDa

1

19

High-throughput

0.479

High

1248179

SPAG5
Sperm-associated antigen 5

1

19

High-throughput

0.479

High

1248180

CK5P2
CDK5 regulatory subunit-associated protein 2

1

18

High-throughput

0.479

High

1248189

TCHP
Trichoplein keratin filament-binding protein

1

15

High-throughput

0.479

High

1248191

CP250
Centrosome-associated protein CEP250

1

19

High-throughput

0.479

High

1248195

UN45A
Protein unc-45 homolog A

1

9

High-throughput

0.479

High

1248196

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1248204

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

7

High-throughput

0.479

High

1248209

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

5

High-throughput

0.479

High

1248211

WRP73
WD repeat-containing protein WRAP73

1

4

High-throughput

0.479

High

1248212

TBK1
Serine/threonine-protein kinase TBK1

1

19

High-throughput

0.479

High

1248213

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

1248218

ANR26
Ankyrin repeat domain-containing protein 26

1

16

High-throughput

0.479

High

1248219

CE164
Centrosomal protein of 164 kDa

1

18

High-throughput

0.479

High

1248221

NINL
Ninein-like protein

1

18

High-throughput

0.479

High

322413

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.458

High

1169003

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.458

High

1177944

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1178806

KIZ
Centrosomal protein kizuna

1

0

High-throughput

0.458

High

1193430

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

1228533

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1248141

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.458

High

1248152

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.458

High

1248172

ISOC1
Isochorismatase domain-containing protein 1

1

0

High-throughput

0.458

High

1248173

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.458

High

1248174

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.458

High

1248181

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

1248182

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

1248184

CCD77
Coiled-coil domain-containing protein 77

1

0

High-throughput

0.458

High

1248188

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

1248198

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

1248199

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.458

High

1248205

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.458

High

401018

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

12

High-throughput

0.445

High

175089

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.437

High

190016

TOX3
TOX high mobility group box family member 3

1

4

High-throughput

0.437

High

588967

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

695752

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

1029499

SRSF2
Serine/arginine-rich splicing factor 2

1

1

High-throughput

0.437

High

1035515

CENPE
Centromere-associated protein E

1

1

High-throughput

0.437

High

1081701

CGNL1
Cingulin-like protein 1

1

17

High-throughput

0.437

High

1150918

TRIPB
Thyroid receptor-interacting protein 11

1

19

High-throughput

0.437

High

1156523

CCDC6
Coiled-coil domain-containing protein 6

1

16

High-throughput

0.437

High

1248151

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.437

High

1248156

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

8

High-throughput

0.437

High

1248186

GPTC1
G patch domain-containing protein 1

1

2

High-throughput

0.437

High

1248187

PCGF1
Polycomb group RING finger protein 1

1

15

High-throughput

0.437

High

1248200

NANOG
Homeobox protein NANOG

1

2

High-throughput

0.437

High

1248203

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

High-throughput

0.437

High

1248210

CING
Cingulin

1

17

High-throughput

0.437

High

1248223

WAC2C
WASH complex subunit 2C

1

1

High-throughput

0.437

High

1143837

TCAL1
Transcription elongation factor A protein-like 1

3

0

High-throughput

0.347

High

1248176

BORC6
BLOC-1-related complex subunit 6

3

0

High-throughput

0.347

High

1248222

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.328

High

1248145

ZC3C1
Zinc finger C3HC-type protein 1

2

0

High-throughput

0.319

High

1103824

TARB1
tRNA

2

0

High-throughput

0.305

High

1248177

CC138
Coiled-coil domain-containing protein 138

2

0

High-throughput

0.305

High

143064

NFIB
Nuclear factor 1 B-type

1

0

High-throughput

0.279

Low

664519

ALAT1
Alanine aminotransferase 1

1

0

High-throughput

0.279

Low

1179801

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1205793

GSAML
Germinal center-associated signaling and motility-like protein

1

0

High-throughput

0.279

Low

1248157

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.279

Low

1248207

RTEL1
Regulator of telomere elongation helicase 1

1

0

High-throughput

0.279

Low

47349

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

1248140

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.268

Low

338341

SC24A
Protein transport protein Sec24A

1

0

High-throughput

0.249

Low

1147621

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

1248137

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.249

Low

1248143

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.249

Low

1248165

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.249

Low

1248192

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

1248208

ABRAL
Costars family protein ABRACL

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025