HitPredict

Interactor 1: GCC2 (Q8IWJ2)
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)
Gene: GCC2

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33853758, 35944360, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1684 Hs			1 708
+	Hs
		1189228 RGPD4_HUMAN (1361-1664): 3.14e-51: 202: 46.46		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		63904 RGPD3_HUMAN (1361-1664): 1.31e-49: 196: 45.23		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		725263 MYH10_HUMAN (697-1684): 5.34e-42: 171: 9.78		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1061279 NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1068692 PLEC_HUMAN (255-1682): 1.43e-31: 138: 10.06		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		725055 MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		828635 CENPF_HUMAN (1-571): 7.48e-20: 99.6: 10.67		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		433200 LAMB1_HUMAN (937-1308): 8.11e-10: 66.2: 21.93		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1350002 DAPLE_HUMAN (582-1406): 5.94e-09: 63.5: 20.77		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1218754 GCC2_HUMAN (1-1684): 8.38e-119: 415: 100.00		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		599624 MYH11_HUMAN (1292-1682): 9.22e-14: 79.2: 8.16		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		152767 RGPD8_HUMAN (1360-1672): 7.35e-73: 272: 47.31		NU153_HUMAN (109-348): 5.07e-09: 61.9: 11.11
+	Hs
		483387 RGPD1_HUMAN (1361-1667): 1.13e-47: 190: 43.60		RBP2_HUMAN (35-380): 3.46e-21: 101: 9.86
+	Hs
		834747 NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82		RBP2_HUMAN (35-380): 3.46e-21: 101: 9.86
+	Hs
		834601 NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82		NU153_HUMAN (109-348): 5.07e-09: 61.9: 11.11