HitPredict

Interactor 1: Q5XGX4 (Q5XGX4)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: rnf185.L

Interactor 2: Q801P8 (Q801P8)
Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa)
Gene: ubqln4.L

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17558393
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Xl			1 599
+	Xl
		1220153 Q5XGX4_XENLA (1-189): 1.12e-64: 198: 100.00		Q6DCM1_XENLA (22-599): 7.24e-125: 381: 59.69
+	Hs
		1391932 RN185_HUMAN (1-189): 2.18e-57: 180: 91.67		UBQL1_HUMAN (1-599): 3.21e-129: 393: 58.35
+	Hs
		1391926 RN185_HUMAN (1-189): 2.18e-57: 180: 91.67		UBQL4_HUMAN (12-599): 9.59e-122: 374: 71.33
+	Hs
		1391929 RN185_HUMAN (1-189): 2.18e-57: 180: 91.67		UBQL2_HUMAN (1-599): 6.3e-113: 352: 53.54
+	Hs
		1420591 TRIM4_HUMAN (27-110): 2.73e-27: 108: 28.57		UBQL2_HUMAN (1-599): 6.3e-113: 352: 53.54
+	Hs
		1089281 TRI26_HUMAN (22-111): 3.14e-26: 106: 30.77		UBQL2_HUMAN (1-599): 6.3e-113: 352: 53.54
+	Hs
		1395632 RN170_HUMAN (15-188): 8.7e-27: 104: 16.76		UBQL2_HUMAN (1-599): 6.3e-113: 352: 53.54
+	At
		1456605 PEX10_ARATH (3-90): 1.62e-23: 97.6: 25.00		DSK2B_ARATH (8-596): 8.43e-86: 279: 28.57
+	At
		1456606 PEX10_ARATH (3-90): 1.62e-23: 97.6: 25.00		DSK2A_ARATH (8-596): 3.79e-84: 274: 28.62
+	Hs
		856886 RNF5_HUMAN (12-154): 1.97e-42: 142: 62.94		BAG6_HUMAN (11-546): 1.05e-62: 226: 14.71
+	Xl
		1220162 Q5XGX4_XENLA (1-189): 1.12e-64: 198: 100.00		Q7ZT10_XENLA (23-302): 1.05e-43: 163: 13.73
+	Hs
		931695 RN185_HUMAN (1-189): 2.18e-57: 180: 91.67		RD23B_HUMAN (23-302): 2.5e-47: 172: 14.46
+	Hs
		856861 TRI11_HUMAN (22-127): 9.1e-26: 104: 24.53		BAG6_HUMAN (11-546): 1.05e-62: 226: 14.71
+	Hs
		623170 RO52_HUMAN (22-111): 2.61e-22: 94.9: 23.33		BAG6_HUMAN (11-546): 1.05e-62: 226: 14.71
+	Xl
		1220159 Q5XGX4_XENLA (1-189): 1.12e-64: 198: 100.00		Q6GQF3_XENLA (23-107): 2.4e-26: 106: 31.40
+	Xl
		1220156 Q5XGX4_XENLA (1-189): 1.12e-64: 198: 100.00		Q6GMC1_XENLA (23-109): 5.97e-26: 105: 28.41
+	Hs
		931661 HLTF_HUMAN (1-158): 2.21e-29: 115: 17.72		RD23B_HUMAN (23-302): 2.5e-47: 172: 14.46
+	Hs
		987161 RN185_HUMAN (1-189): 2.18e-57: 180: 91.67		RS27A_HUMAN (23-109): 5.97e-26: 105: 28.41
+	Hs
		931604 TRI39_HUMAN (28-107): 5.4e-25: 102: 27.50		RD23A_HUMAN (22-326): 1.88e-41: 155: 15.34
+	Dm
		583728 Q9W3I9_DROME (7-87): 2.22e-21: 92.2: 36.91		RS27A_DROME (23-109): 5.47e-26: 106: 27.27