HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 23033263, 27131364, 31495888, 32398829, 37059091
Identification Methods affinity chromatography technology, x-ray crystallography, two hybrid, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BTB~BTB, Slx4~Slx4
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0003677 - DNA binding
and 16 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1834
Hs

1 1834
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+ Dm
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024