Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: MUS81 (Q96NY9)
Crossover junction endonuclease MUS81 (EC 3.1.22.-)
Gene: MUS81

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.767

The method score is based on:

Property Details
Experiments 25416956, 21516116, 25224045, 28514442, 29850896, 32296183, 24012755, 25533185, 23033263, 23623386, 29892012, 31495888, 32398829, 37071664, 37059091, 19596235, 22902628, 21240275, 19595721, 19596236 and 3 others

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Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, anti bait coimmunoprecipitation, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0046872 - metal ion binding
and 1 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1834
Hs

1 551
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024