Interactor 1: PLCG1 (Q62077)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1
Interactor 2: SOS1 (Q62245)
Son of sevenless homolog 1 (SOS-1) (mSOS-1)
Gene: SOS1
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15953601 |
| Identification Methods | pull down |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~RhoGEF, RhoGEF~SH3_1, SH3_1~SOS1_NGEF_PH |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005829 - cytosol GO:0007173 - epidermal growth factor receptor signaling pathway GO:0098978 - glutamatergic synapse |
| Homologous interactions | 6 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
