HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: LRFN4 (Q80XU8)
Leucine-rich repeat and fibronectin type-III domain-containing protein 4
Gene: LRFN4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	16828986
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 636
+	Mm
		503541 DLG4_MOUSE (1-724): 0: 653: 100.00		LRC4B_MOUSE (16-370): 6.49e-57: 206: 25.00
+	Rn
		723879 DLG4_RAT (1-724): 0: 654: 99.45		LRFN2_RAT (2-313): 3.7e-26: 116: 15.17
+	Mm
		1223589 DLG4_MOUSE (1-724): 0: 653: 100.00		LRFN2_MOUSE (2-313): 5.81e-26: 115: 15.17
+	Mm
		1180771 DLG4_MOUSE (1-724): 0: 653: 100.00		LRFN1_MOUSE (2-141): 4.3e-25: 112: 19.44
+	Mm
		1223632 DLG4_MOUSE (1-724): 0: 653: 100.00		LRC4C_MOUSE (5-82): 2.49e-09: 62.3: 19.75
+	Rn
		1192937 DLG3_RAT (20-724): 0: 571: 62.87		LRFN2_RAT (2-313): 3.7e-26: 116: 15.17
+	Mm
		999790 DLG3_MOUSE (20-724): 0: 571: 62.87		LRFN2_MOUSE (2-313): 5.81e-26: 115: 15.17
+	Mm
		1281877 DLG1_MOUSE (5-724): 0: 561: 68.98		LRFN2_MOUSE (2-313): 5.81e-26: 115: 15.17
+	Mm
		1180772 DLG1_MOUSE (5-724): 0: 561: 68.98		LRFN1_MOUSE (2-141): 4.3e-25: 112: 19.44
+	Rn
		1192936 DLG1_RAT (5-724): 0: 550: 67.73		LRFN2_RAT (2-313): 3.7e-26: 116: 15.17
+	Mm
		999793 DLG3_MOUSE (20-724): 0: 571: 62.87		LRC4C_MOUSE (5-82): 2.49e-09: 62.3: 19.75
+	Hs
		1245251 PALS1_HUMAN (52-184): 5.33e-13: 74.3: 14.93		LRFN4_HUMAN (17-636): 3.6e-130: 398: 96.61
+	Hs
		1122257 SCRIB_HUMAN (58-243): 7.61e-25: 113: 40.72		VASN_HUMAN (15-516): 8.56e-61: 216: 22.96
+	Hs
		1122330 SCRIB_HUMAN (58-243): 7.61e-25: 113: 40.72		LGR4_HUMAN (5-183): 2.53e-14: 78.8: 21.11
+	Hs
		1122310 SCRIB_HUMAN (58-243): 7.61e-25: 113: 40.72		LRIG1_HUMAN (281-577): 9.66e-14: 76.9: 15.49
+	Mm
		1297656 DLG2_MOUSE (225-570): 1.26e-17: 89.7: 17.32		LRC4C_MOUSE (5-82): 2.49e-09: 62.3: 19.75