HitPredict

Interactor 1: TIF1B (Q62318)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-A-interacting protein) (KRIP-1) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: Trim28

Interactor 2: TIF1B (Q62318)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-A-interacting protein) (KRIP-1) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: Trim28

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 37372979, 10562550
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PHD~PHD, zf-B_box~zf-B_box, zf-B_box~zf-RING_5
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000792 - heterochromatin
GO:0001701 - in utero embryonic development
and 30 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 834
Mm

1 834
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+ Mm
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+ Ce
+ Dr
+ Hs
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Last updated: 11Aug2025