Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 27903803, 29599493, 10669754, 32296183, 34795231, 36880596, 31839598, 16778193, 9671498, 9230084, 16540467, 22773875, 22493164, 12438698, unassigned1304, 20211142, 9294197
Identification Methods enzymatic study, affinity chromatography technology, x-ray crystallography, pull down, far western blotting, two hybrid, proximity labelling technology, cross-linking study, two hybrid array, validated two hybrid and 1 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4~zf-C3HC4
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0001666 - response to hypoxia
GO:0002230 - positive regulation of defense response to virus by host
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
and 77 others

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Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 882
Hs

1 882
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Last updated: 11Aug2025