HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: HOME1 (Q86YM7)
Homer protein homolog 1 (Homer-1)
Gene: HOMER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030424 - axon GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Hs			1 354
+	Hs
		1227653 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		EVL_HUMAN (1-160): 1.26e-28: 116: 21.82
+	Hs
		896555 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		VASP_HUMAN (1-146): 3.2e-28: 115: 22.36
+	Hs
		1191424 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		GRDN_HUMAN (158-347): 6.53e-26: 111: 22.28
+	Hs
		1227621 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		EP15R_HUMAN (65-303): 4.12e-18: 87.8: 11.94
+	Hs
		1226865 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		MRCKG_HUMAN (183-349): 3.71e-10: 63.5: 17.24
+	Hs
		1227122 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		DLG5_HUMAN (107-349): 5.12e-10: 63.1: 13.81
+	Hs
		1211878 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		FKB15_HUMAN (72-353): 9e-09: 59.3: 14.34
+	Hs
		1092885 STRN3_HUMAN (14-603): 3.47e-97: 316: 12.99		FKB15_HUMAN (72-353): 9e-09: 59.3: 14.34
+	Hs
		984141 GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30		GRDN_HUMAN (158-347): 6.53e-26: 111: 22.28
+	Hs
		587609 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		DESP_HUMAN (95-342): 9.33e-09: 59.3: 12.30
+	Hs
		587613 GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30		DESP_HUMAN (95-342): 9.33e-09: 59.3: 12.30
+	Hs
		845334 LIS1_HUMAN (99-438): 4.66e-48: 175: 14.72		DLG5_HUMAN (107-349): 5.12e-10: 63.1: 13.81
+	Mm
		1000461 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		VASP_MOUSE (1-146): 6.61e-31: 122: 21.66
+	Hs
		587585 LIS1_HUMAN (99-438): 4.66e-48: 175: 14.72		DESP_HUMAN (95-342): 9.33e-09: 59.3: 12.30
+	Mm
		1000410 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		EVL_MOUSE (1-153): 1.51e-27: 113: 21.52
+	Mm
		1243464 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		FKB15_MOUSE (101-354): 1.83e-24: 107: 16.92
+	Hs
		587823 NLE1_HUMAN (441-607): 8.65e-43: 162: 20.34		DESP_HUMAN (95-342): 9.33e-09: 59.3: 12.30
+	Mm
		1221958 A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25		EP15R_MOUSE (65-303): 7.95e-15: 77.8: 10.82
+	Hs
		1211892 POC1A_HUMAN (482-607): 3.81e-29: 121: 23.02		FKB15_HUMAN (72-353): 9e-09: 59.3: 14.34
+	Hs
		587723 WDR5B_HUMAN (174-393): 1.14e-21: 98.2: 12.96		DESP_HUMAN (95-342): 9.33e-09: 59.3: 12.30